China Animal Husbandry and Veterinary Medicine ›› 2025, Vol. 52 ›› Issue (1): 341-350.doi: 10.16431/j.cnki.1671-7236.2025.01.031
• Preventive Veterinary Medicine • Previous Articles
WANG Lei1,2, LIANG Lin2, LUO Runqi1,2, LIANG Ruiying2, HU Dandan1, SI Hongbin1, DING Jiabo2, DI Wenda1, TANG Xinming2
Received:2024-05-09
Published:2024-12-30
CLC Number:
WANG Lei, LIANG Lin, LUO Runqi, LIANG Ruiying, HU Dandan, SI Hongbin, DING Jiabo, DI Wenda, TANG Xinming. Research Advancement in Chicken Infectious Anemia Vaccine[J]. China Animal Husbandry and Veterinary Medicine, 2025, 52(1): 341-350.
| [1] 郭雨欣,李晓齐,王永强,等.鸡传染性贫血病毒抑制干扰素的研究进展[J].中国兽医杂志,2023,59(3):84-90. GUO Y X,LI X Q,WANG Y Q,et al.Research progress of Chicken infectious anemia virus in inhibiting interferon[J].Chinese Journal of Veterinary Medicine,2023,59(3):84-90.(in Chinese) [2] SONG H,KIM H,KWON Y,et al.Genetic characterization of Chicken infectious anaemia viruses isolated in Korea and their pathogenicity in chicks[J].Frontiers in Cellular Infection Microbiology,2024,14:1333596. [3] DAVIDSON I,KEDEM M,BOROCHOVITZ H,et al.Chicken infectious anemia virus infection in Israeli commercial flocks:Virus amplification,clinical signs,performance,and antibody status[J].Avian Diseases,2004,48(1):108-118. [4] ROSARIO K,BREITBART M,HARRACH B,et al.Revisiting the taxonomy of the family Circoviridae:Establishment of the genus Cyclovirus and removal of the genus Gyrovirus[J]. Archives of Virology,2017,162(5):1447-1463. [5] DAI M,HUANG Y,WANG L,et al.Genomic sequence and pathogenicity of the Chicken anemia virus isolated from chicken in Yunnan province,China[J]. Frontiers in Veterinary Science,2022,18:9:860134. [6] ELTAHIR Y M,QIAN K,JIN W,et al.Molecular epidemiology of Chicken anemia virus in commercial farms in China[J].Virology Journal,2011,8:145. [7] 吕 钊,马国明,牛登云,等.2021年中国部分地区鸡传染性贫血病毒VP1基因遗传变异分析[J].中国家禽,2023,45(4):64-68. LYU Z,MA G M,NIU D Y,et al.Genetic variation analysis of VP1 gene of Chicken infectious anemia virus in some areas of China in 2021[J].China Poultry,2023,45(4):64-68.(in Chinese) [8] 金 松,孟宪臣,薛亚梅,等.我国部分地区黄羽肉鸡群鸡传染性贫血病病毒的流行病学调查及致病性分析[J].中国家禽,2022,44(2):29-35. JIN S,MENG X C,XUE Y M,et al.Epidemiological investigation and pathogenicity analysis of Chicken infectious anemia virus in Yellow-feathered broilers in some areas of China[J].China Poultry,2022,44(2):29-35.(in Chinese) [9] CHEN J,YUAN X,MA Z,et al.Chicken infectious anemia virus (CIAV) VP1 antagonizes type Ⅰ interferon (IFN-Ⅰ) production by inhibiting TBK1 phosphorylation[J]. Virus Research,2023,2:327:199077. [10] LIU X,XI D,XU A,et al.Chicken anemia virus VP1 negatively regulates type Ⅰ interferon via targeting interferon regulatory factor 7 of the DNA-sensing pathway[J]. Journal of Poultry Science,2023,102(1):102291. [11] FANG L,ZHEN Y,SU Q,et al.Efficacy of CpG-ODN and Freund’s immune adjuvants on antibody responses induced by Chicken infectious anemia virus VP1,VP2,and VP3 subunit proteins[J]. Journal of Poultry Science,2019,98(3):1121-1126. [12] NATESAN S,KATARIA J M,DHAMA K,et al.Anti-neoplastic effect of Chicken anemia virus VP3 protein (apoptin) in Rous sarcoma virus-induced tumours in chicken[J].Journal of General Virology,2006,87(Pt 10):2933-2940. [13] LOS M,PANIGRAHI S,RASHEDI I,et al.Apoptin,a tumor-selective killer[J].Biochimica et Biophysica Acta,2009,1793(8):1335-1342. [14] 黄 英.鸡传染性贫血病毒衣壳蛋白的重组表达及其间接ELISA方法的建立[D].武汉:华中农业大学,2020. HUANG Y.Recombinant expression of Chicken infectious anemia virus capsid protein and establishment of indirect ELISA method[D].Wuhan:Huazhong Agricultural University,2020.(in Chinese) [15] 解慧梅.江苏省鸡传染性贫血病血清流行病学调查及病原分离与鉴定[D].扬州:扬州大学,2018. XIE H M.Seroepidemiological investigation and pathogen isolation and identification of Chicken infectious anemia in Jiangsu province[D].Yangzhou:Yangzhou University,2018.(in Chinese) [16] 崔现兰,幸桂香,吴东来,等.鸡传染性贫血病病毒的鉴定[J].中国畜禽传染病,1992,6:3-5. CUI X L, XING G X, WU D L, et al. Identification of Chicken infectious anemia virus[J]. Chinese Journal of Animal Infectious Diseases, 1992,6:3-5. (in Chinese) [17] FUJIWARA A,HORII W,SANO J,et al.Invasion of Chicken anemia virus in specific-pathogen-free chicken flocks and its successful elimination from the colony[J].Veterinary Sciences,2024,11(7):329. [18] WANG X W,FENG J,JIN J X,et al.Molecular Epidemiology and pathogenic characterization of novel Chicken infectious anemia viruses in Henan province of China[J]. Frontiers in Veterinary Science,2022,28:9:871826. [19] 桑明山.鸡传染性贫血病的危害及防控措施[J].中国畜牧业,2024,8:83-84. SANG M S.Harm and prevention measures of infectious anemia of chickens[J].China Animal Industry,2024,8:83-84.(in Chinese) [20] 甄 岳.鸡传染性贫血病毒与新城疫弱毒疫苗LaSota株对SPF鸡的协同致病作用[D].泰安:山东农业大学,2019. ZHEN Y.Synergistic pathogenic effect of Infectious anemia virus and attenuated Newcastle disease vaccine LaSota strain on SPF chickens[D].Tai’an:Shandong Agricultural University,2019.(in Chinese) [21] SU Q,LI Y,ZHANG Y,et al.Newcastle disease virus-attenuated vaccine LaSota played a key role in the pathogenicity of contaminated exogenous virus[J]. Veterinary Research,2018,49(1):80. [22] ZHANG J,MA L,LI T,et al.Synergistic pathogenesis of Chicken infectious anemia virus and J subgroup of Avian leukosis virus[J].Journal of Poultry Science,2021,100(11):101468. [23] 杨 明,崔治中,苏 帅,等.鸡传染性贫血病毒与马立克氏病病毒共感染SPF鸡群免疫抑制协同作用的研究[J].中国动物传染病学报,2010,18(4):1-5. YANG M,CUI Z Z,SU S,et al.Study on the synergistic effect of immunosuppression in SPF chickens co-infected with Infectious anemia virus and Marek’s disease virus[J].China Journal of Animal Infectious Diseases,2010,18(4):1-5.(in Chinese) [24] 王笑梅,王秀荣,邱 冬,等.雏鸡混合感染IBDV与CAV的研究[J].中国预防兽医学报,2000,22(5):2-5. WANG X M,WANG X R,QIU D,et al.Study on mixed infection of IBDV and CAV in chicks[J]. Chinese Journal of Preventive Veterinary Medicine,2000,22(5):2-5.(in Chinese) [25] 金文杰,崔治中,刘岳龙,等.传染性法氏囊病病料中MDV、CAV、REV的共感染检测[J].中国兽医学报,2001,21(1):6-9. JIN W J,CUI Z Z,LIU Y L,et al.Co-infection detection of MDV,CAV and REV in infectious bursal disease[J].Chinede Journal of Veterinary Science,2001,21(1):6-9.(in Chinese) [26] 许 杰.鸡传染性贫血病及其防控[J].畜牧兽医科技信息,2021,7:202. XU J.Infectious anemia in chicken and its prevention and control[J].Chinese Journal of Animal Husbandry and Veterinary,2021,7:202.(in Chinese) [27] 薛冬梅.鸡传染性贫血的流行病学、临床特征、实验室诊断和防控措施[J].现代畜牧科技,2021,3:129-130. XUE D M.Epidemiology,clinical characteristics,laboratory diagnosis and prevention and control measures of infectious anemia in chickens[J]. Modern Animal Husbandry Science and Technology,2021,3:129-130.(in Chinese) [28] VIELITZ E,CONRAD C,VOSS M,et al.Vaccination against infectious anemia of poultry (CAA)--Results of field studies[J].Deutsche Tierarztliche Wochenschrift,1991,98(4):144-147. [29] 张 鹏,张承新,丁 斌,等.鸡传染性贫血病免疫程序的合理制定与评估[J].家禽科学,2022,6:59-61. ZHANG P,ZHANG C X,DING B,et al.Reasonable formulation and evaluation of immunization program for infectious anemia in chickens[J].Poultry Science,2022,6:59-61.(in Chinese) [30] 徐少珠,张国丽,丘成文,等.鸡传染性喉气管炎疫苗研究进展[J].广东畜牧兽医科技,2023,48(4):35-41. XU S Z,ZHANG G L,QIU C W,et al.Research progress of chicken infectious laryngotracheitis vaccine[J].Guangdong Journal of Animal and Veterinary Science,2023,48(4):35-41.(in Chinese) [31] 王秀荣,王笑梅,吴东来,等.鸡贫血病灭活疫苗免疫后雏鸡免疫状况研究[J].中国预防兽医学报,2000,S1:147-152. WANG X R,WANG X M,WU D L,et al.Study on the immune status of chicks immunized with inactivated vaccine against chicken anemia[J].Chinese Journal of Preventive Veterinary Medicine,2000,S1:147-152.(in Chinese) [32] ZHANG X,WU B,LIU Y,et al.Assessing the efficacy of an inactivated Chicken anemia virus vaccine[J].Vaccine,2015,33(16):1916-1922. [33] 李 岳.鸡传染性贫血病毒流行毒株生物学特性及致弱研究[D].北京:中国农业科学院,2021. LI Y.Study on biological characteristics and attenuation of infectious Anemia virus epidemic strain[D].Beijing:Chinese Academy of Agricultural Sciences,2021.(in Chinese) [34] 汪梦竹,蒲飞洋,赵泽阳,等.新型疫苗的研究进展[J].畜牧与兽医,2022,54(9):141-147. WANG M Z,PU F Y,ZHAO Z Y,et al.Research progress of new vaccines[J].Animal Husbandry and Veterinary Medicine,2022,54(9):141-147.(in Chinese) [35] LEE M S,HSEU Y C,LAI G H,et al.High yield expression in a recombinant E.coli of a codon optimized Chicken anemia virus capsid protein VP1 useful for vaccine development[J].Microbial Cell Factories,2011,23:10:56. [36] 陈绍平.鸡贫血病毒VP1、VP2基因在毕赤酵母中的共表达及重组蛋白的分析[D].雅安:四川农业大学,2008. CHEN S P.Co-expression of Chicken anemia virus VP1 and VP2 genes in Pichia pastoris and analysis of recombinant protein[D].Ya’an:Sichuan Agricultural University,2008.(in Chinese) [37] KOCH G,VAN ROOZELAAR D J,VERSCHUEREN C A,et al.Immunogenic and protective properties of Chicken anaemia virus proteins expressed by Baculovirus[J].Vaccine,1995,13(8):763-770. [38] SHEN S Y,CHANG W C,YI H H,et al.Development of a subunit vaccine containing recombinant Chicken anemia virus VP1 and pigeon IFN-γ[J]. Veterinary Immunology and Immunopathology,2015,167(3-4):200-204. [39] TSENG T Y,LIU Y C,HSU Y C,et al.Preparation of Chicken anemia virus (CAV) virus-like particles and chicken interleukin-12 for vaccine development using a Baculovirus expression system[J]. Pathogens,2019,8(4):262. [40] 陆 印,朱晶平.DNA疫苗技术[J].白城师范学院学报,2011,25(5):18-20. LU Y,ZHU J P.DNA vaccine technology[J].Journal of Baicheng Normal University,2011,25(5):18-20.(in Chinese) [41] MOEINI H,OMAR A R,RAHIM R A,et al.Development of a DNA vaccine against Chicken anemia virus by using a bicistronic vector expressing VP1 and VP2 proteins of CAV[J].Comparative Immunology and Microbiology and Infectious Diseases,2011,34(3):227-236. [42] MOEINI H,OMAR A R,RAHIM R A,et al.Improving the potency of DNA vaccine against Chicken anemia virus (CAV) by fusing VP1 protein of CAV to Marek’s disease virus (MDV) type-1 VP22 protein[J]. Journal of Virology,2011,14:8:119. [43] SAWANT P M,DHAMA K,RAWOOL D B,et al.Development of a DNA vaccine for chicken infectious anemia and its immunogenicity studies using high mobility group box 1 protein as a novel immunoadjuvant indicated induction of promising protective immune responses[J].Vaccine,2015,33(2):333-340. [44] 杨明珠,陈晓春,宋佳诚,等.重组动物疱疹病毒活载体疫苗的构建与应用研究进展[J].中国畜牧兽医,2022,49(1):338-351. YANG M Z,CHEN X C,SONG J C,et al.Research progress on construction and application of recombinant animal herpesvirus live vector vaccine[J]. China Animal Husbandry & Veterinary Medicine,2022,49(1):338-351.(in Chinese) [45] 谢金文,沈 旭,林初文,等.新城疫病毒载体的应用研究进展[J].中国人兽共患病学报,2013,29(9):919-923. XIE J W,SHEN X,LIN C W,et al.Research progress in application of Newcastle disease virus vector[J].Chinese Journal of Zoonoses,2013,29(9):919-923.(in Chinese) [46] CHELLAPPA M M,DEY S,PATHAK D C,et al.Newcastle disease virus vectored chicken infectious anaemia vaccine induces robust immune response in chickens[J]. Viruses,2021,13(10):1985. [47] 张仁舟,杨松涛,夏咸柱.重组痘苗病毒载体研究进展[J].动物医学进展,2009,30(1):57-61. ZHANG R Z,YANG S T,XIA X Z.Research progress of recombinant Vaccinia virus vector[J].Progress in Veterinary Medicine,2009,30(1):57-61.(in Chinese) [48] CONRAD S J,MAYS J K,HEARN C J,et al.Targeted ablation of exon 2 of the Avian leukosis virus-A (ALV-A) receptor gene in a chicken fibroblast cell line by CRISPR abrogates ALV-A infection[J].Avian Diseases,2023,67(1):102-107. [49] XU X,XUE C,LIU X,et al.A novel recombinant attenuated Newcastle disease virus expressing H9 subtype hemagglutinin protected chickens from challenge by genotype Ⅶ virulent Newcastle disease virus and H9N2 Avian influenza virus[J].Veterinary Microbiology,2019,228:173-180. [50] SHEN X,HAO Y,WANG S,et al.Sequential heterologous immunization with COVID-19 vaccines induces broader neutralizing responses against SARS-CoV-2 variants in comparison with homologous boosters[J]. Vaccine,2023,41(45):6645-6653. [51] ZHOU Y,LI S,BI S,et al.Long-lasting protective immunity against H7N9 infection is induced by intramuscular or CpG-adjuvanted intranasal immunization with the split H7N9 vaccine[J].International Immunopharmacology,2020,78:106013. [52] LIU Y,SÁNCHEZ-OVANDO S,CAROLAN L,et al.Superior immunogenicity of mRNA over adenoviral vectored COVID-19 vaccines reflects B cell dynamics independent of anti-vector immunity:Implications for future pandemic vaccines[J].Vaccine,2023,41(48):7192-7200. [53] ZHANG W,JIANG Y,HE Y,et al.Lipid carriers for mRNA delivery[J].Acta Pharmaceutica Sinica B,2023,13(10):4105-4126. [54] KIM S H,SAMAL S K.Heterologous prime-boost immunization of Newcastle disease virus vectored vaccines protected broiler chickens against highly pathogenic Avian influenza and Newcastle disease viruses[J]. Vaccine,2017,35(33):4133-4139. [55] WU X,ZHAI X,LAI Y,et al.Construction and immunogenicity of Novel chimeric virus-like particles bearing antigens of Infectious bronchitis virus and Newcastle disease virus[J]. Viruses,2019,11(3):254. [56] FATOBA A J,ADELEKE V T,MAHARAJ L,et al.Design of a multiepitope vaccine against Chicken anemia virus disease[J].Viruses,2022,14(7):1456. [57] 梁瑞英,索静霞,梁 琳,等.艾美耳球虫的遗传操作:平台建立、应用与展望[J].畜牧兽医学报,2024,55(8):3362-3373. LIANG R Y, SUO J X, LIANG L, et al. Genetic manipulation of Eimeria: Platform development, application,and perspective[J]. Acta Veterinaria et Zootechnica Sinica, 2024,55(8): 3362-3373. (in Chinese) [58] LIU Q,LIU X,ZHAO X,et al.Live attenuated anticoccidial vaccines for chickens[J].Trends in Parasitology,2023,39(12):1087-1099. [59] TANG X,LIU X,SUO X.Towards innovative design and application of recombinant Eimeria as a vaccine vector[J].Infection and Immunity,2020,88(5):e00861-19. [60] TANG X,YIN G,QIN M,et al.Transgenic Eimeria tenella as a vaccine vehicle:Expressing TgSAG1 elicits protective immunity against Toxoplasma gondii infections in chickens and mice[J].Scientific Reports,2016,6:29379. [61] CLARK J D,OAKES R D,REDHEAD K,et al. Eimeria species parasites as novel vaccine delivery vectors:Anti-Campylobacter jejuni protective immunity induced by Eimeria tenella-delivered CjaA[J].Vaccine,2012,30(16):2683-2688. [62] MARUGAN-HERNANDEZ V,COCKLE C,MACDONALD S,et al.Viral proteins expressed in the protozoan parasite Eimeria tenella are detected by the chicken immune system[J]. Parasit and Vectors,2016,9(1):463. [63] YU Y,TANG X,DUAN C,et al.Microneme-located VP2 in Eimeria acervulina elicits effective protective immunity against Infectious bursal disease virus[J].Infection and Immunity,2024,92(2):e0045623. |
| [1] | JI Yongchen, ZHAO Jingwen, WU Huiguang. Research Progress on Atypical Porcine Pestivirus [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(12): 5075-5083. |
| [2] | YANG Li-cong, SU Xia, ZHU Rui-hao, ZHOU Hong-zhuan, XU Fu-zhou, YANG Bing, SUN Ji-guo. Development of a SYBR Green Ⅰ Real-time PCR Method for Detection of Chicken Infectious Anemia Virus [J]. , 2015, 42(4): 859-864. |
| [3] | GUO Cui-li, ZHANG Chun-hong, GUO Peng-ju, ZHANG Jian-feng, SHEN Hai-yan, PAN Jia-qiang. Development of TaqMan Fluorescence Quantitative PCR Assay for Detection of Chicken Infectious Anemia Virus [J]. , 2014, 41(12): 45-49. |
| [4] | ZHAO Feng, LI Xue-hua, LIN Shi-wu, GUO Wen-jie, YANG Ming, XU Zeng-qiang, QIU Jian-dong, LI Jin, ZHANG Rui, LI Yan-dong. Prokaryotic Expression and Immunogenicity Analysis of Chicken Infectious Anemia Virus vp1 Gene [J]. , 2013, 40(8): 34-38. |
| [5] | CUI Peng-peng, GAO Hong-lei, LI Kai, GAO Li, GAO Yu-long, QI Xiao-le, WANG Xiao-mei. Construction and Characterization of Yeast Two-hybrid cDNA Expression Library of MDCC-MSB1 [J]. , 2013, (5): 22-25. |
| [6] | WANG Jing-ru, YANG Xiao-jing. Establishment of a Nested PCR Assay for Detection of Chicken Infectious Anemia Virus [J]. , 2013, 40(4): 55-58. |
| Viewed | ||||||
|
Full text |
|
|||||
|
Abstract |
|
|||||
