胰岛素样生长因子结合蛋白3和胰岛素样生长因子结合蛋白5基因在内蒙古白绒山羊皮肤中的表达研究

Abstract

Abstract: This experiment was conducted to study the expression effect of insulin-like growth factor-binding protein(IGFBP) of Inner Mongolia Cashmere goat skin in different developmental stage. The expression of IGFBP-1 to IGFBP-6 in different developmental stage of hair follicle cycle was measured by Real-time PCR. Furthermore, the hair growth cycle was changed by implanting melatonin to identify the role of IGFBP-1 to IGFBP-6 gene, the high expression of the binding protein. The results showed that IGFBP-3 and IGFBP-5 both were expressed in different developmental stage of hair follicle cycle, however, the expression of IGFBP-5 gene presented more regular. The results indicated that IGFBP-5 might be a major regulatory factor in the process of hair follicle development of Inner Mongolia Cashmere goat.

Key words: Inner Mongolia Cashmere goat; IGFBP-3; IGFBP-5; hair follicle cycle

CLC Number:

YU Xin-lei, CAI Ting, JU Hong-li, YANG Hui-ru, XIAO Hong-mei, LIU Zhi-hong, WANG Quan-xi, WANG Zhi-xin, LI Jin-quan. Study on Expression of Insulin-like Growth Factor-binding Protein -3 and -5 (IGFBP-3 and IGFBP-5) in the Skin of Inner Mongolia Cashmere Goat[J]. , 2013, 40(10): 1-5.

References

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Study on Expression of Insulin-like Growth Factor-binding Protein -3 and -5 (IGFBP-3 and IGFBP-5) in the Skin of Inner Mongolia Cashmere Goat

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