p63基因及其与肿瘤的关系研究进展

Abstract

Abstract: p63 gene is one of tumor suppressor gene p53 family members. It displays high homology to p53 gene. The structure of p63 is more complex than p53. It has two different promoters and many different introns splicing modes, p63 gene encodes many kinds of p63 isoform proteins. These p63 isoforms perform their diverse biological functions in different tissues and different developmental phases. This paper introduces researching progress of p63 genetic structure, biological functions and the relationships with tumors.

Key words: p63; isoform; structure; function; tumor

CLC Number:

S857.4

YU Tian-ming, HAN Li-mei, LIU Jia. Research Progress of p63 Gene and its Relationship with Tumor[J]. , 2012, 39(7): 90-93.

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Research Progress of p63 Gene and its Relationship with Tumor

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