应用体内诱导抗原技术筛选病原菌体内表达基因的研究进展

Abstract

Abstract: An overview of in vivo induced antigen technology (IVIAT) will be presented, including a discussion of the advantages and limitations of this method. In vivo induced antigen technology (IVIAT) is a technique that identifies pathogen antigens that are immunogenic and expressed in vivo during animal infection. Over 20 different microbial pathogens have been or are known to be currently studied with this method. IVIAT is complementary to other techniques that identify genes and their products expressed in vivo. Genes and gene pathways identified by IVIAT may play roles in virulence or pathogenesis during animal infection, and may be appropriate for inclusion in therapeutic, vaccine or diagnostic applications.

Key words: ivi gene; IVIAT; principal; application; prospect

CLC Number:

Q939.9

LI Shu-guang, ZHANG Na, WANG Jin-liang, ZHAO Lei, CHEN Jin-long, MIAO Li-zhong, SHEN Zhi-qiang. Overview of Identification of Ivi Genes Uniquely Expressed during the Infection with Pathogenic Bacteria Using IVIAT[J]. , 2012, 39(7): 87-89.

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Overview of Identification of Ivi Genes Uniquely Expressed during the Infection with Pathogenic Bacteria Using IVIAT

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