Abstract: To study therapeutic experiment of compound Shenqin on sickness dog of myocarditis parvovirus caused by artifical infection. The dogs were divided into control group,model group, positive control group,compound Shenqin group. Animal model was established with canine parvovirus. And canine parvovirus disease was prevented with compound Shenqin,experimental animals the heart rate and electrocardiogram was determinated by the biological signal acquisition system of ECG technology. Then completion of animal experiments,the animals were killed and the heart was paraffin-embedded,tissue section,microscopic examination. The results showed that after infection the third day,the heart rate and disorder rate of electrocardiogram of dog in model group was increased,serious damage to myocardial;the heart rate of dog in the compound Shenqin group retains normally,the disorder rate of electrocardiogram were significantly lower than dog in the model group,cardiac tissue compared with the control group no significantly difference. After experimental animals infected the fifth day,the death rate of dog in the model group is up to 100 percent. But the control group is not appear to death. The protective rate of compound Shenqin group is up to 80 percent. The protective rate of positive control group is up to 70 percent. The result showed that compound Shenpin can be effective in preventing myocarditis canine parvovirus disease in dog.

Key words: compound Shenqin; canine parvovirus; histopathology; heart rate; ECG