猪圆环病毒Ⅱ型流行病学新特点及致病机理研究进展

Abstract

Abstract: Porcine circovirus type 2 (PCV2) is the main causative agent of porcine circovirus diseases, which is responsible for the greatly economic losses in the swine industry. The rate of nucleotide substitution within PCV2 is high, which keep the highest rate yet recorded for a single-stranded DNA virus. Although the oronasal route is considered the most likely route of infection, PCV2 can be shed in nasal, tonsillar, bronchial and ocular secretions, as well as in faeces, saliva, urine milk and semen. Pigs with PMWS have greater amounts of PCV2 in their serum and shed large quantities of virus than do non-affected pigs. The piglets which have high antibodies against PCV2 do not develop a viraemia until these antibodies wane. PMWS- affected pigs have depletion of T- and B-lymphocytes, factors that are currently thought to influence the outcome of PCV2 infection include 4 main areas of focus: virus, host, coinfections, and immune modulation.

Key words: porcine circovirus; epidemiology; pathogenesis

CLC Number:

S852.65

WANG Xian-wen, YAO Si-xin, WANG Li-rong, HANG Bai-lin, LIU Xing-you. Recent Advances in the Epidemiology and Pathogenesis of Diseases Caused by Porcine Circovirus Type 2[J]. , 2012, 39(12): 190-194.

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Recent Advances in the Epidemiology and Pathogenesis of Diseases Caused by Porcine Circovirus Type 2

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