Abstract: The pathways of Chinese herbal medicine in fracture healing are not very well understood. Therefore, the objective of the present study was to evaluate the effects of one compound Chinese herbal medicine on rabbits radius fracture healing using indexes(such as the serum Ca, P, serum ALP, and X-ray of bone fracture). 48 healthy mature rabbits were selected to build standard defect models, and randomly divided into experimental groups and control groups. The control rabbits were given standard diet. Experimental rabbits were fed with standard diet plus Chinese herbal medicine (2.5 g/kg) every day. The detection was performed on the 2, 4, 6 and 8 weeks after operation. The results of the study showed that the level of serum Ca, P, the activity of AKP and X-ray appearances for taking Chinese herbal medicine after fracture were significantly higher than that of the control. In conclusion, composite Chinese herbs might shorten the time to union, improve the quality of fracture healing and be beneficial to the fracture healing.

Key words: Chinese herbal medicine; fracture healing; rabbit; biochemical indexes of the blood; X-ray