氟苯尼考与盐酸土霉素体外联合抑菌效果研究

›› 2011, Vol. 38 ›› Issue (7): 201-203.

• 疾病防治 • Previous Articles Next Articles

Studies on the Combined Antibacterial Activity of Florfenicol and Oxytetracycline Hydrochloride in vitro

ZHOU Wen-zhong¹, BI Ke-dong¹, ZOU Ben-ge², LI Hong³, ZOU Ming¹, ZHANG Qi-di¹

1. College of Veterinary Medicine, Qingdao Agricultural University, Qingdao 266109, China;2. College of Haidu,Qingdao Agricultural University, Laiyang 265200, China;3. Veterinary Station in Guandao Town, Qixia 265316, China

Received:2010-12-20 Revised:1900-01-01 Online:2011-07-20 Published:2011-07-20

Abstract

Abstract: The susceptibility test of Florfenicol and Oxytetracycline Hydrochloride on six strains of Escherichia coli and Salmonella was carried out by the broth dilution checkerboard method in order to study the combined antibacterial effect in clinical application in vitro. The results suggested that the MIC of single drug on the standard strains of Escherichia coli and Salmonella was 1 to 8 μg/mL, on the clinical strains was 64-128 μg/mL. The FIC of drug combination was 0.5, 0.75, 1.5, 0.5, 0.75, 1.0; there were four strains appeared additive effect while the other two strains appeared synergistic and irrelevant effect.

Key words: Florfenicol; Oxytetracycline Hydrochloride; drug combination

CLC Number:

S859.79⁺6

ZHOU Wen-zhong;BI Ke-dong;ZOU Ben-ge;LI Hong;ZOU Ming;ZHANG Qi-di. Studies on the Combined Antibacterial Activity of Florfenicol and Oxytetracycline Hydrochloride in vitro[J]. , 2011, 38(7): 201-203.

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Studies on the Combined Antibacterial Activity of Florfenicol and Oxytetracycline Hydrochloride in vitro

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