Abstract: To observe Chawu Mei, aloe and so on, 12 Chinese herbal medicines in the water extract of chicken pathogenic Escherichia coli O78 inhibition effects. Ebony, aloe, et al, boiling water to get the water extract of traditional Chinese medicine obtained solution was determined on the chicken disease Escherichia coli O78 minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC), of 12 Chinese herbal medicines for drug susceptibility testing, and better in vitro antibacterial effect of a single taste of Chinese medicine in vivo tests. Results showed that Platycodon grandiflorum, Forsythia, rhubarb, peony, Atractylodes almost no activity against chicken pathogenic Escherichia coli, ebony, aloe vera, Pulsatilla good antibacterial activity, including ebony, Pulsatilla and Aloe vera extract on chicken pathogenic Escherichia coli O78 of the MIC were 2.57, 2.06 and 2.31 mg/mL. Ebony, aloe vera, and the bulbul has a certain resistance to the role of chicken pathogenic Escherichia coli, for the development of new anti-chicken pathogenic Escherichia coli lay the theoretical basis for the drug.

Key words: traditional Chinese medicine; Escherichia coli O78; antibacterial