Kisspeptins/GPR54系统及其在动物性发育中的作用

›› 2009, Vol. 36 ›› Issue (12): 93-96.

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Kisspeptins/GPR54 System and Puberty Onset

ZHANG Ying^1,2, YU Jian-feng¹, GU Zhi-liang¹

(1.Department of Life Science and Technology, Changshu Institute of Technology, Changshu 215500, China;2.College of Preclinical Medicine and Biological Science, Soochow University, Suzhou 215123, China)

Received:1900-01-01 Revised:1900-01-01 Online:2009-12-20 Published:2009-12-20
Contact: GU Zhi-liang

Abstract

Abstract: The activation of GnRH pulsatile release is a key step of animal sexual development. Studies show that kisspeptins/GPR54 system, playing a pivotal role in activation of GnRH pulsatile release, is a regulator of sexual development onset. Studies regarding the intracellular signaling pathways on kisspeptins/GPR54 confirm that kisspeptins can activate a wide variety of signals via GPR54 to exert the other roles. Additionally, some factors such as photoperiod and energy reserve affect animal sexual development remarkably.

Key words: GnRH; HPG; kisspeptins/GPR54 system; signaling pathway

CLC Number:

S813.3

ZHANG Ying;YU Jian-feng;GU Zhi-liang. Kisspeptins/GPR54 System and Puberty Onset[J]. , 2009, 36(12): 93-96.

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