›› 2007, Vol. 34 ›› Issue (8): 137-141.

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Advances in the Research of Mammalian Defensins

LONG Jing, DU Lixin   

  1. National Center for Molecular Genetics and Breeding of Animal Institute of Animal Science(CAAS), Beijing 100094, China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-08-20 Published:2007-08-20

Abstract: Defensins are peptidic components of the innate immune system of plants and animals. In mammals, defensins have evolved to have a central function in the host defense properties of granulocytic leukocytes, mucosal surfaces, skin and epithelial. This review focuses on the region and distribution of defensin, the characteristic of molecular structure, biological activity, functions and application of mammalian defensins.

Key words: defensin; biological activity; application

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