L-瓜氨酸对游泳力竭小鼠生长性能及血清生化指标影响的研究

doi:10.16431/j.cnki.1671-7236.2020.04.008

Abstract

Abstract: Effects of adding different doses of L-citrulline (L-Cit) in drinking water on the growth performance and serum biochemical indexes of swimming exhausted Kunming mice was studied in this paper.36 weaned females with average weight of (14.58±0.77) g were selected and randomly divided into 3 groups with 6 replicates in each group.The mice in control group drank from tap water,and 0.5% and 1% of L-Cit were added in the drinking water for test groupⅠand Ⅱ,respectively.The trial lasted 21 d.Every 3 d,the mice were weighed in an empty stomach and then swam with weight loading in (31±2)℃ bucket until exhausted.Blood was collected from the eyeballs at day 21.The results showed that:Compared with control group,at the day 6,9 and 12,the body weights of the female mice in test groups Ⅰ and Ⅱ increased by 12.88% (P < 0.05),20.30% (P < 0.01),7.99% (P < 0.05) and 21.27% (P < 0.01),24.47% (P < 0.01),19.46% (P < 0.01) respectively.And it increased by 13.71% (P < 0.01) at day 15 in test group Ⅱ.The serum activity of anti superoxide anion free radical (ASAFR) increased by 31.49% (P < 0.01) in test group Ⅰ.The serum activity of GSH-Px and inhibit hydroxyl free radical (IHFR) ability were increased by 54.35%(P < 0.01)and 13.10%(P < 0.01)in test group Ⅱ,respectively.Compared with the control group and test groupⅠ,the serum levels of serum albumin (ALB)content were respectively increased by 13.16% (P < 0.01) and 6.28% (P < 0.01).In conclusion,Adding L-Cit in drinking water could improve the growth performance and antioxidant capacity,increase serum total protein (TP) and albumin contents in mice after exercise,and adding 0.1% L-Cit (69.09 mg/d) was better.

Key words: L-citrulline; mice; growth performance; antioxidant indexes

CLC Number:

S816.7

ZHAO Guodong, LI Xiaobin, LI Tingting, CHEN hui, MA Chen, ZENG Wushuang, ZANG Changjiang. Study of L-citrulline on Growth Performance of Swimming Exhausted and Serum Biochemical Effect of Mice[J]. China Animal Husbandry and Veterinary Medicine, 2020, 47(4): 1035-1040.

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Study of L-citrulline on Growth Performance of Swimming Exhausted and Serum Biochemical Effect of Mice

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