›› 2018, Vol. 45 ›› Issue (9): 2591-2599.doi: 10.16431/j.cnki.1671-7236.2018.09.032

Previous Articles     Next Articles

Research Progress on the Flagella of Campylobacter jejuni

LIU Mingyue, CHENG Guyue, WANG Xu, DAI Menghong, HAO Haihong, YUAN Zonghui   

  1. National Reference Laboratory of Veterinary Drug Residues, Huazhong Agricultural University, Wuhan 430070, China
  • Received:2018-02-01 Online:2018-09-20 Published:2018-09-26

Abstract:

Campylobacter jejuni is a major pathogen cause of foodborne diarrhea that affects both humans and animals,and the infection rate is increased year by year.Flagella is an unique structure of the bacterial,it is associated with the motility of bacterial,and it also plays an important role in the pathogenicity.Many studies have shown that the pathogenicity of Campylobacter jejuni has a great relationship with the colonization and invasion of flagella in host epithelical cells and the production of toxins.This paper reviewed the research progress on the structure,function,regulatory mechanism and relates genes expression of flagella in Campylobacter jejuni,summed up the influence of known gene deletion mutation of Campylobacter jejuni on flagella to explore the pathogenic mechanism of Campylobacter jejuni from molecular level in order to offer theoretical basis to reduce the infection rate.

Key words: Campylobacter jejuni; flagella; pathogenicity; flagellin

CLC Number: