犬黄体功能调控机制研究进展

doi:10.16431/j.cnki.1671-7236.2017.09.009

Abstract

Abstract:

Significant differences can be found in the physiology construction and functional performance of canine corpus luteum from the other domestic animal species, and the most interesting characteristic is the lack of an acute luteolytic mechanism. It is a multifactorial process that luteinization of canine is regulated by PRL, LH and PGE₂, and the luteolysis is insensitive to PGF_2α. The remaining canine corpus luteum plays an important role in bitch reproductive activities, and the steroid hormone from it through autocrine or paracrine is the same important to pregnancy and the estrus cycle. It is still unknown about the mechanism of regression of canine corpus luteum, however, there are several hypotheses including the passive regression mechanism. Moreover, corpus luteum is one of the few tissues (organs) which includes all three parts formation, maintenance and regression of the life cycle, and it is very important for the research of inflammatory reaction, carcinogenesis and apoptosis. In this review, the advanced progress of formation and regression of canine corpus luteum were summarized, which would provide theoretical basis and research background to study the molecular mechanism in this filed.

Key words: canine; corpus luteum; luteinization; luteolysis; mechanism

CLC Number:

S858.292

SONG Zi-yu, FAN Chao-yue, ZHONG You-gang. Research Progress on Regulatory Mechanisms of Canine Corpus Luteum Function[J]. , 2017, 44(9): 2598-2602.

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Research Progress on Regulatory Mechanisms of Canine Corpus Luteum Function

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