绒山羊次级毛囊基因表达滞后性的转录组分析

doi:10.16431/j.cnki.1671-7236.2016.07.006

Abstract

Abstract:

Hair follicle is capable of self-renew and its growth cycle is a dynamic process.In order to investigate the vary of differential expression genes in the Nei Mongol cashmere goat hair follicles during anagen,the mRNA expression levels of different genes in skin hair follicles were detected from June to October using Illumina technology.Evaluation of transcriptomes was undertaken to understand the time-course gene expression involved in both follicle types.The samples were collected from June to October.Most of differentially expressed genes appeared between July to August in primary hair follicle (PF) and between August to September in secondary hair follicle (SF).Seven differentially expressed genes,FAM83C,LOC102185501,FYCO1,CTTNBP2NL,C6orf132,KRTAP29-1 and CRYBG3 were identified.Their expression demonstrated similar trends at different months of cashmere growth cycle and the SF postpone for about one month.These findings indicated the hysteresis in SF gene regulation comparing with PF,and could provide the useful theoretical basis for the molecular mechanism of cashmere regeneration.

Key words: cashmere goat; hair follicle; hysteresis; transcriptome

CLC Number:

Q344⁺.13

JI Xiao-yang, LIU Bin, BAI Xue, WANG Hong, FU Shao-yin, CANG Zhen-wei, WU Jiang-hong, ZHANG Wen-guang. Transcriptome Survey Reveals Hysteresis in Secondary Hair Follicle for Gene Regulation in Cashmere Goat[J]. , 2016, 43(7): 1694-1701.

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Transcriptome Survey Reveals Hysteresis in Secondary Hair Follicle for Gene Regulation in Cashmere Goat

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