Abstract: The study was carried out to study the effects of Lonicera fulvotomentosa extract on growth performance, diarrhea rate and anti-oxidation performance in mice.90 mice were randomly divided into five groups:Blank group, experimental groups Ⅰ, Ⅱ, Ⅲ and control group.The blank group was fed with basal diet, the experimental groups were added the 0.02, 0.04 and 0.06 mg/g BW of Lonicera fulvotomentosa extract to basal diet, and the diet of control group was added the colistin sulfate observing the diarrhea rate in mice with folium sennae perfusion.The results showed that comparing with blank group, the finial weight of mice in experimental groups Ⅱ, Ⅲ and control group were significantly improved (P<0.05);The Lonicera fulvotomentosa extract had effects on growth performance in the experimental groups, there was no significant effects on the liver weight (P<0.05);The diarrhea rate in the experimental groups were decreased with the increase of the concentration of Lonicera fulvotomentosa extract, and the diarrhea rate in the control group was significantly lower than blank group (P<0.05).Compared with the blank group, the activity of GSH-Px and CAT in experimental groups (except group Ⅰ) were increased, and the serum SOD activity in experimental group Ⅲ was significantly increased (P<0.05).In conclusion, the growth performance and anti-oxidation performance of mice were increased while the diarrhea rate was decreased by adding the Lonicera fulvotomentosa extract, and adding 0.06 mg/g BW concentration had the best effects.

Key words: Lonicera fulvotomentosa; extract; mice; growth performance; anti-oxidation performance