同日龄不同体重羔羊十二指肠形态功能的比较研究

doi:10.16431/j.cnki.1671-7236.2015.08.024

Abstract

Abstract: To understand the effect of intestinal digestion and absorption on the growth and development of lambs.60 5-month and healthy lambs were selected as the study subjects which were F1 generation hybridized by Altay sheep × Teksaier sheep and were fed in the same rearing conditions and had the same weaning date.And then, 8 lambs with significant weight differences were equally divided into HBW group and LBW group, the former with average weight (37.20±2.80)kg and the latter with average weight (28.24±3.75)kg.Measurements were to be performed for the differences in the morphological indicators of villus in duodenum, digestive enzyme activity in duodenum and sodium glucose cotransporter 1 (SGLT1) and glucose transporter 2 (GLUT2) in the lambs'mucosa.The results showed that the villus height and crypt depth of duodenum in HBW group were significantly lower than that in LBW group (P< 0.05), there were no significant differences in the mucosal thickness and V/C between two groups (P> 0.05);The amylase activity in HBW group was significantly higher than that in LBW group (P< 0.05), the activities of maltase, lactase and sucrase in HBW group were extremely significantly higher than that in LBW group (P< 0.01), there were no significant differences in the activities of lipase and protease between two groups (P> 0.05);The expression amount of SGLT1 in HBW group was significantly higher than that in LBW group (P< 0.05), the expression amount of GLUT2 in HBW group was extremely significantly higher than that in LBW group (P< 0.01).In conclusion, there was close correlation between the weight increment of the lambs and digestive and absorptive functions of duodenum, and that further research and study need to be conducted to have a better understanding of the regulating mechanism of molecular biology for digestive enzyme and glucose transporter.

Key words: lamb; growth rate; small intestinal mucosa; amylase; sucrase; glucose transfer protein

CLC Number:

S826

MA Xue-lian, WANG Jin-quan, ZHANG Xiao-hong, YAO Gang. Study on the Morphology and Fuction of the Duodenum in Lambs with Same Weaning Age but Different Body Weight[J]. , 2015, 42(8): 2091-2097.

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Study on the Morphology and Fuction of the Duodenum in Lambs with Same Weaning Age but Different Body Weight

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