雄性生殖系统抗氧化研究进展

doi:10.16431/j.cnki.1671-7236.2016.05.031

摘要/Abstract

摘要： 雄性生殖道代谢活跃,活性氧(reactive oxygen species,ROS)的产生不可避免,低浓度的ROS对哺乳动物生殖具有基础性作用,但ROS的过度累积必然会使精子发生氧化损伤而影响其受精能力。因此精子对抗氧化应激的保护机制非常重要,作者就目前公认的雄性生殖系统中抗氧化酶及氧化还原系统的研究现状进行综述,为更好地开展雄性动物生理和病理学研究提供借鉴。

关键词: 精子; 精液; 氧化应激; 抗氧化; 生殖

Abstract: It is believed that active metabolism in male reproductive tract is contributed to production of ROS (reactive oxygen species).Low physiological ROS plays a fundamental role in mammalian reproduction, but the excessive accumulation of potentially damaging ROS can affect the function of sperm.Thus, it is important to maintain normal reproductive ability by a protective mechanism against oxidative stress.Here, we review the progress of antioxidant enzymes and redox systems in male reproductive systems, in order to provide references for physiology and pathology researches in male animals.

Key words: spermatozoa; semen; oxidative stress; antioxidants; reproduction

中图分类号:

S814

范晓梅, 张家新. 雄性生殖系统抗氧化研究进展[J]. , 2016, 43(5): 1329-1334.

FAN Xiao-mei, ZHANG Jia-xin. Research Progresses on Anti-oxidation in Male Reproductive Systems[J]. , 2016, 43(5): 1329-1334.

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