›› 2013, Vol. 40 ›› Issue (9): 225-228.

• 经验交流 • 上一篇    下一篇

附睾特异谷胱甘肽过氧化物酶基因调控的研究进展

张国林1, 李振1, 高晋生2, 曹宁贤2, 张春香1   

  1. 1. 山西农业大学动物科技学院, 山西太谷 030801;
    2. 山西省畜禽繁育工作站, 山西太原 030002
  • 收稿日期:2013-02-01 出版日期:2013-09-20 发布日期:2013-09-18
  • 通讯作者: 张春香
  • 作者简介:张国林(1989-),男,山东人,硕士生,研究方向:动物营养与繁殖生理学。
  • 基金资助:
    山西农业大学博士基金(200708)。

Research Progress on the Regulation of Epididymal Specific Glutathione Peroxidase (GPx5) Gene

ZHANG Guo-lin1, LI Zhen1, GAO Jin-sheng2, CAO Ning-xian2, ZHANG Chun-xiang1   

  1. 1. College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China;
    2. Livestock Breeding Station of Shanxi Province, Taiyuan 030002, China
  • Received:2013-02-01 Online:2013-09-20 Published:2013-09-18

摘要: 附睾特异谷胱甘肽过氧化物酶(epididymal specific glutathione peroxidase,GPx5)可保护精子免受氧化应激,维持精子遗传信息的完整性,促进精子发育成熟,其重要生理功能在提高动物繁殖力上有着不可替代的作用,但其基因调控转录表达的机制尚不明确。现作者主要对基因表达特性、表达调控和转录调控等内容进行综述。

关键词: 附睾; 附睾特异谷胱甘肽过氧化物酶; 氧化应激; 基因调控

Abstract: Epididymal specific glutathione peroxidase (GPx5) protected sperms from oxidative stress, maintained the integrity of sperm genetic information and promoted sperms to develop, its physiological functions played an irreplaceable role in improving animal reproduction. But the mechanism of its gene expression regulation of transcription was not yet clear. Based on the achievements the concerning literature had been made, the study had carried on the summary of characteristics, expression and regulation of gene expression and transcription regulation etc.

Key words: epididymis; epididymal specific glutathione peroxidase; oxidative stress; gene regulation

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