[1] DUBOS R,SCHAEDLER R W,COSTELLO R,et al.Indigenous,normal,and autochthonous flora of the gastrointestinal tract[J].Journal of Experimental Medicine,1965,122(1):67-76. [2] SAVAGE D C.Microbial ecology of the gastrointestinal tract[J].Annual Reviews in Microbiology,1977,31(1):107-133. [3] CUMMINGS J H,MACFARLANE G T.Colonic microflora:Nutrition and health[J].Nutrition,1997,13(5):476-478. [4] ROBERFROID M,BORNET F,BOULEY C E,et al.Colonic microflora:Nutrition and health[J].Nutrition,1995,53(5):127-130. [5] CHOCT M.Managing gut health through nutrition[J].British Poultry Science,2009,50(1):9-15. [6] CHERVONSKY A V.Influence of microbial environment on autoimmunity[J].Nature Immunology,2010,11(1):28-35. [7] HOOPER L V,LITTMAN D R,MACPHERSON A J.Interactions between the microbiota and the immune system[J].Science,2012,336(6086):1268-1273. [8] 祁玉丽,孙印石,李珊珊.植物多糖对肠道微生态的作用研究进展[J].中国微生态学杂志,2018,30(4):489-494. QI Y L,SUN Y S,LI S S.Research progress of plant polysaccharides on intestinal microbiome[J].Chinese Journal of Microecology,2018,30(4):489-494.(in Chinese) [9] 杨利娜,边高瑞,朱伟云,等.单胃动物肠道微生物菌群与肠道免疫功能的相互作用[J].微生物学报,2014,54(5):480-486. YANG L N,BIANG G R,ZHU W Y,et al.Interactions between the microbiota and the intestinal monogastric animal gut immune function:A review[J].Acta Microbiologica Sinica,2014,54(5):480-486.(in Chinese) [10] CASTILLO M,MART N-OR E S,ANGUITA M,et al.Adaptation of gut microbiota to corn physical structure and different types of dietary fibre[J].Livestock Science,2007,109(1-3):149-152. [11] ABRIOUEL H,BENOMAR N,COBO A,et al.Characterization of lactic acid bacteria from naturally-fermented Manzanilla Aloreña green table olives[J].Food Microbiology,2012,32(2):308-316. [12] LITVAK Y,BYNDLOSS M X,TSOLIS R M,et al.Dysbiotic Proteobacteria expansion:A microbial signature of epithelial dysfunction[J].Current Opinion in Microbiology,2017,39(10):1-6. [13] ARENAS-PADILLA M,DUARTE-GUTI RREZ J L,MATA-HARO V.Bifidobacterium animalis ssp.lactis Bb12 induces IL-10 through cell membrane-associated components via TLR 2 in swine[J].Journal of Applied Microbiology,2018,125(6):1881-1889. [14] YANG J,QIAN K,WANG C,et al.Roles of probiotic lactobacilli inclusion in helping piglets establish healthy intestinal inter-environment for pathogen defense[J].Probiotics and Antimicrobial Proteins,2018,10(2):243-250. [15] ZHANG W,MA C,XIE P,et al.Gut microbiota of newborn piglets with intrauterine growth restriction have lower diversity and different taxonomic abundances[J].Journal of Applied Microbiology,2019,127(2):354-369. [16] YANG Q,HUANG X,ZHAO S,et al.Structure and function of the fecal microbiota in diarrheic neonatal piglets[J].Environmental Microbiology,2017,8(3):502-515. [17] BAN-TOKUDA T,MAEKAWA S,MIWA T,et al.Changes in faecal bacteria during fattening in finishing swine[J].Anaerobe,2017,47(10):188-193. [18] FANG S,XIONG X,SU Y,et al.16S rRNA gene-based association study identified microbial taxa associated with pork intramuscular fat content in feces and cecum lumen[J].BMC Microbiology,2017,17(1):162-171. [19] CHEN X,XU J,REN E,et al.Co-occurrence of early gut colonization in neonatal piglets with microbiota in the maternal and surrounding delivery environments[J].Anaerobe,2018,49(2):30-40. [20] 李德发.猪的营养[M].北京:中国农业大学出版社,2003. LI D F.Nutrition of Pigs[M].Beijing:China Agricultural University Press,2003.(in Chinese) [21] PLUSKE J.Invited review:Aspects of gastrointestinal tract growth and maturation in the pre-and postweaning period of pigs[J].Journal of Animal Science,2016,94(3):399-411. [22] SPLICHALOVA A,SLAVIKOVA V,SPLICHALOVA Z,et al.Preterm life in sterile conditions:A study on preterm,germ-free piglets[J].Frontiers in Immunology,2018,9(2):220-232. [23] DE GOFFAU M C,LAGER S,SOVIO U,et al.Human placenta has no microbiome but can contain potential pathogens[J].Nature,2019,1(7):329-334. [24] 宋连喜,鄂禄祥,高明,等.猪和兔胚胎胃肠道菌群的初步研究[J].中国兽医杂志,2007,43(10):24-26. SONG L X,E L X,GAO M,et al.Preliminary study on gastrointestinal flora of pig and rabbit embryos[J].Chinese Journal of Veterinary Medicine,2007,43(10):24-26.(in Chinese) [25] UNDERWOOD M A,GILBERT W M,SHERMAN M P.Amniotic fluid:Not just fetal urine anymore[J].Journal of Perinatology,2005,25(5):341-348. [26] JOST T,LACROIX C,BRAEGGER C P,et al.Vertical mother-neonate transfer of maternal gut bacteria via breastfeeding[J].Environmental Microbiology,2014,16(9):2891-2904. [27] DOMINGUEZ-BELLO M G,COSTELLO E K,CONTRERAS M,et al.Delivery mode shapes the acquisition and structure of the initial microbiota across multiple body habitats in newborns[J].Proceedings of the National Academy of Sciences,2010,107(26):11971-11975. [28] CHEN W,MI J,LV N,et al.Lactation stage-dependency of the sow milk microbiota[J].Frontiers in Microbiology,2018,9(5):945-957. [29] MART N V,MALDONADO-BARRAG N A,MOLES L,et al.Sharing of bacterial strains between breast milk and infant feces[J].Journal of Human Lactation,2012,28(1):36-44. [30] WIYAPORN M,THONGSONG B,KALANDAKANOND-THONGSONG S.Growth and small intestine histomorphology of low and normal birth weight piglets during the early suckling period[J].Livest Science,2013,158(1-3):215-222. [31] WANG X,TSAI T,DENG F,et al.Longitudinal investigation of the swine gut microbiome from birth to market reveals stage and growth performance associated bacteria[J].Microbiome,2019,7(1):109-127. [32] ZENG M,INOHARA N,NU EZ G.Mechanisms of inflammation-driven bacterial dysbiosis in the gut[J].Mucosal Immunology,2017,10(1):18-26. [33] ALAIN B P E,CHAE J P,BALOLONG M P,et al.Assessment of fecal bacterial diversity among healthy piglets during the weaning transition[J].Journal of General & Applied Microbiology,2014,60(4):140-146. [34] WANG T,TENG K,LIU G,et al.The functions and mechanisms of microecological agents in weaning piglet intestine[J].Scientin Sinica Vitae,2019,49(2):97-107. [35] LI Y,GUO Y,WEN Z,et al.Weaning stress perturbs gut microbiome and its metabolic profile in piglets[J].Scientific Reports,2018,8(1):1-12. [36] WANG X,TSAI T,DENG F,et al.Longitudinal investigation of the swine gut microbiome from birth to market reveals stage and growth performance associated bacteria[J].Microbiome,2019,7(1):109-127. [37] PARKER A,LAWSON M A,VAUX L,et al.Host-microbe interaction in the gastrointestinal tract[J].Environmental Microbiology,2018,20(7):2337-2353. [38] CHEN L,XU Y,CHEN X,et al.The maturing development of gut microbiota in commercial piglets during the weaning transition[J].Frontiers in Microbiology,2017,8(9):1-13. [39] MATHEW A,ROBBINS C,CHATTIN S,et al.Influence of galactosyl lactose on energy and protein digestibility,enteric microflora,and performance of weanling pigs[J].Journal of Animal Science,1997,75(4):1009-1016. [40] MURASE K,WATANABE T,ARAI S,et al.Characterization of pig saliva as the major natural habitat of Streptococcus suis by analyzing oral,fecal,vaginal,and environmental microbiota[J].PLoS One,2019,14(4):e0215983. [41] ZHAO W,WANG Y,LIU S,et al.The dynamic distribution of porcine microbiota across different ages and gastrointestinal tract segments[J].PLoS One,2015,10(2):1-13. [42] WU G D,CHEN J,HOFFMANN C,et al.Linking long-term dietary patterns with gut microbial enterotypes[J].Science,2011,334(6052):105-108. [43] ZHANG L,MU C,HE X,et al.Effects of dietary fibre source on microbiota composition in the large intestine of suckling piglets[J].FEMS Microbiology Letters,2016,363(14):1-6. [44] METZLER B,MOSENTHIN R.A review of interactions between dietary fiber and the gastrointestinal microbiota and their consequences on intestinal phosphorus metabolism in growing pigs[J].Asian-Australasian Journal of Animal Sciences,2008,21(4):603-615. [45] LIU B,WANG W,ZHU X,et al.Response of gut microbiota to dietary fiber and metabolic interaction with SCFAs in piglets[J].Frontiers in Microbiology,2018,9(28):23-44. [46] LUO Y,CHEN H,YU B,et al.Dietary pea fibre alters the microbial community and fermentation with increase in fibre degradation-associated bacterial groups in the colon of pigs[J].Journal of Animal Physiology and Animal Nutrition,2018,102(1):e254-e261. [47] CHENG G,HAO H,XIE S,et al.Antibiotic alternatives:The substitution of antibiotics in animal husbandry?[J].Frontiers in Microbiology,2014,5(217):1-15. [48] 杨伟平,王建刚,曹斌云.猪肠道微生物群落组成变化及其影响因素[J].中国畜牧杂志,2017,53(1):12-16. YANG W P,WANG J G,CAO B Y.Composition and influence factors of pigs' gut microbial community[J].Chinese Journal of Animal Science,2017,53(1):12-16.(in Chinese) [49] MIKKELSEN M S,JENSEN M G,NIELSEN T S.Barley beta-glucans varying in molecular mass and oligomer structure affect cecal fermentation and microbial composition but not blood lipid profiles in hypercholesterolemic rats[J].Food & Function,2017,8(12):4723-4732. [50] 陈庆菊,刘金艳,卢昌文,等.饲粮添加β-葡聚糖对断奶仔猪生长性能和肠道微生物区系的影响[J].动物营养学报,2018,30(11):4712-4720. CHEN Q J,LIU J Y,LU C W,et al.Effects of dietary β-glucan on growth performance and intestinal microflora of weaned piglets[J].Chinese Journal of Animal Nutrition,2018,30(11):4712-4720.(in Chinese) [51] 吴俊,许二学,刘强.日粮添加异麦芽寡糖对断奶仔猪生长性能、抗氧化和免疫性能及肠道微生物含量的影响[J].中国饲料,2018,29(12):46-50. WU J,XU E X,LIU Q,et al.Effects of dietary supplementation of isomalto oligosaccharide on growth performance,antioxidant capacity,immunity and gut microbiota of weaning pigs[J].China Feed,2018,29(12):46-50.(in Chinese) [52] 崔艺燕,马现永.酵母多糖的生物学功能及其对仔猪肠道健康的影响[J].动物营养学报,2018,30(3):857-864. CUI Y Y,MA X Y.Biological function of yeast polysaccharide and its effect on piglet's gut health[J].Chinese Journal of Animal Nutrition,2018,30(3):857-864.(in Chinese) [53] LI P,NIU Q,WEI Q,et al.Microbial shifts in the porcine distal gut in response to diets supplemented with Enterococcus Faecalis as alternatives to antibiotics[J].Scientific Reports,2017,7(2):1-10. [54] 刘颖,王海斌,周刚,等.抗生素对仔猪肠道微生物的影响[J].动物营养学报,2017,29(8):2912-2922. LIU Y,WANG H B,ZHOU G,et al.Effects of antibiotics on intestinal microorganisms of piglets[J].Chinese Journal of Animal Nutrition,2017,29(8):2912-2922.(in Chinese) [55] YU M,MU C,YANG Y,et al.Increases in circulating amino acids with in-feed antibiotics correlated with gene expression of intestinal amino acid transporters in piglets[J].Amino Acids,2017,49(9):1587-1599. [56] NEUMAN H,FORSYTHE P,UZAN A,et al.Antibiotics in early life:Dysbiosis and the damage done[J].FEMS Microbiology Reviews,2018,42(4):489-499. [57] 姚浪群,萨仁娜,佟建明,等.安普霉素对仔猪肠道微生物及肠壁组织结构的影响[J].畜牧兽医学报,2003,34(3):250-257. YAO L Q,SA R N,Tong J M,et al.Effect of apramycin on intestinal flora and intestinal morphology of piglets[J].Journal of Animal Husbandry and Veterinary Medicine,2003,34(3):250-257.(in Chinese) [58] LIN J,HUNKAPILLER A A,LAYTON A C,et al.Response of intestinal microbiota to antibiotic growth promoters in chickens[J].Foodborne Pathogens & Disease,2013,10(4):331-337. [59] KUANG Y,WANG Y,ZHANG Y,et al.Effects of dietary combinations of organic acids and medium chain fatty acids as a replacement of zinc oxide on growth,digestibility and immunity of weaned pigs[J].Animal Feed Science & Technology,2015,208(5):145-157. [60] ZHU C,LV H,CHEN Z,et al.Dietary zinc oxide modulates antioxidant capacity,small intestine development,and jejunal gene expression in weaned piglets[J].Biological Trace Element Research,2017,175(2):331-338. [61] 彭鹏,陈思佳,蒋再慧,等.多孔氧化锌对断奶仔猪粪便中微量元素含量,盲肠内容物与粪便中短链脂肪酸含量及肠道菌群多样性的影响[J].动物营养学报,2018,30(12):5221-5229. PENG P,CHEN S J,JIANG Z H,et al.Effects of porous zinc oxide on fecal microelement contents,short chain fatty acid contents in cecum content and feces and intestinal bacterial diversity of weaned piglets[J].Chinese Journal of Animal Nutrition,2018,30(12):5221-5229.(in Chinese) [62] 梅绍锋.高铜对断奶仔猪的促生长和微生态效应研究[D].雅安:四川农业大学,2009. MEI S F.Study on the growth promoting and microecological effects of high copper on weaned piglets[D].Ya'an:Sichuan Agricultural University,2009.(in Chinese) [63] CHENG S,MAO H,RUAN Y,et al.Copper changes intestinal microbiota of the cecum and rectum in female mice by 16S rRNA gene sequencing[J].Biological Trace Element Research,2019,5(1):1-11. [64] 孔祥杰,姜海龙,蔡维北,等.黄芪茎叶对断奶仔猪盲肠微生物区系的影响[J].中国畜牧杂志,2017,53(3):117-120. KONG X J,JIANG H L,CAI W B,et al.Effect of astragalus stem plant on the microflora in gut of weaned piglets[J].Chinese Journal of Animal Science,2017,53(3):117-120.(in Chinese) [65] YE G,QIU Y,HE X L,et al.Effect of two macrocephala flavored powder supplementation on intestinal morphology and intestinal microbiota in weaning pigs[J].International Journal of Clinical & Experimental Medicine,2015,8(1):1504-1514. [66] MICHIELS J,MISSOTTEN J A M,FREMAUT D,et al.In vitro characterisation of the antimicrobial activity of selected essential oil components and binary combinations against the pig gut flora[J].Animal Feed Science & Technology,2009,151(1):111-127. [67] 姚继明,孟秀丽,吕锋,等.复合有机酸酸化剂对断奶仔猪生长性能及其肠道微生物菌群的影响[J].饲料工业,2017,38(2):11-16. YAO J M,MENG X L,LYU F,et al.The influences of compound organic acid acidifier on the growth performance and intestinal flora of weaned piglets[J].Feed Industry,2017,38(2):11-16.(in Chinese) |