›› 2012, Vol. 39 ›› Issue (6): 200-204.

• 流行病防治 • 上一篇    下一篇

10种中药体外抗H1N1猪流感病毒的效果研究

徐振娜1,2, 王丙云2, 计慧琴2, 陈志胜2, 陈胜峰2, 杨鸿2, 何永明2, 陈金顶1   

  1. 1. 华南农业大学兽医学院,广东广州 510642;
    2. 佛山科学技术学院动物医学系,广东佛山 528231
  • 修回日期:2011-11-18 出版日期:2012-06-20 发布日期:2012-07-02
  • 通讯作者: 王丙云,博士,教授,硕士生导师。E-mail:bywang63@163.com E-mail:bywang63@163.com
  • 作者简介:徐振娜(1987-),女,广东人,硕士生,研究方向:兽医微生物学与免疫学。
  • 基金资助:
    佛山市科技专项发展基金(2009030);广东省佛山市禅城区科技开发专项资金项目(2011A1063)。

Efficacy of Ten Chinese Herbal Medicine against H1N1 Swine Influenza Virus in Vitro

XU Zhen-na1,2, WANG Bing-yun2, JI Hui-qin2, CHEN Zhi-sheng2, CHEN Sheng-feng2, YANG Hong2, HE Yong-ming2, CHEN Jin-ding1   

  1. 1. College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China;
    2. Faculty of Veterinary Medicine, Foshan Science and Technology University, Foshan 528231, China
  • Revised:2011-11-18 Online:2012-06-20 Published:2012-07-02

摘要: 为了观察10种中药抗猪流感病毒的效果,本试验通过先加中药再加病毒、先加病毒再加中药以及中药和病毒混合后一起加3种加药方式,采用鸡胚培养法和红细胞凝集(HA)试验研究了桂枝等10种中药在体外抗猪流感病毒的效果。然后,将有显著效果的中药筛选出来,测定其治疗指数(TI)和半数有效量(ED50)。试验结果表明,在3种加药方式中,桂枝和麻黄抗猪流感病毒的效果最为显著。

关键词: 猪流感病毒; 中药; 鸡胚

Abstract: To observe the efficacy of ten Chinese herbal medicine against swine influenza virus, cinnamomi ramulus etc ten Chinese herbal medicine were investigated the antiviral action by chicken embryo culture and hemagglutination test in three ways to add medicine. Then, the Chinese herbal medicine that had predominance efficacy was selected to determine their therapeutic index (TI) and 50% effective dose (ED50). The results showed that: cinnamomi ramulus and herbal ephedrae have most predominance efficacy against swine influenza virus.

Key words: swine influenza virus; Chinese herbal medicine; chicken embryo

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