›› 2011, Vol. 38 ›› Issue (1): 222-226.

• 流行病防治 • 上一篇    下一篇

布鲁氏菌病的研究进展

毛景东1,王景龙2,3,杨艳玲2,3   

  1. (1.内蒙古民族大学动物科技学院,内蒙古通辽 028042; 2.吉林大学畜牧兽医学院,吉林长春 130062;3.中国人民解放军军事兽医研究所第十一所,吉林长春 130062)
  • 收稿日期:1900-01-01 修回日期:2010-09-09 出版日期:2011-01-01 发布日期:2011-01-01
  • 通讯作者: 杨艳玲

The Research Advancement of Brucellosis

MAO Jing-dong1, WANG Jing-long2,3, YANG Yan-ling2,3   

  1. (1.College of Animal Science and Technology, Inner Mongolia University for the Nationalites,Tongliao 028042, China;2.College of Animal Medicine and Veterinary Medicine, Jilin University, Changchun 130062, China;3. The Eleventh Institute of the Academy of Military Medical Sciences of PLA, Changchun 130062, China)
  • Received:1900-01-01 Revised:2010-09-09 Online:2011-01-01 Published:2011-01-01
  • Contact: YANG Yan-ling

摘要:

布病,尤其是由羊种布鲁氏菌引起的布病,目前是世界上最常见的一种人兽共患传染病,全世界每年报道的布病病例超过500万。布鲁氏菌已经被CDC列为B类病原体,成为潜在的生物武器。布鲁氏菌也是最常见的实验室源性病原体。布病的流行地域在不断变化,每年都有新发地和复发地的报道。除了那些牛布病已经根除的国家,布病仍然在许多国家的人和动物中存在。全世界由于布病给动物产品及公共卫生安全而带来的经济损失是巨大的。虽然许多有效的疫苗正在用于动物免疫,但是还没有理想的人用疫苗可以使用。动物布病的控制将显著降低人布病的发生。

关键词: 布鲁氏菌病; 人兽共患病; 研究进展

Abstract: Brucellosis, especially caused by Brucella melitensis, remains one of the most common zoonotic diseases worldwide with more than 500000 human cases reported annually. The bacterial pathogen is classified by the CDC as a category (B) pathogen that has potential for development as a bio-weapon. Brucella spp. is considered as the most common laboratory-acquired pathogens. The geographical distribution of brucellosis is constantly changing with new foci emerging or re-emerging. The disease occurs worldwide in both animals and humans, except in those countries where bovine brucellosis has been eradicated. The worldwide economic losses due to brucellosis are extensive not only in animal production but also in human health.Although a number of successful vaccines are being used for immunization of animals, no satisfactory vaccine against human brucellosis is available. When the incidence of brucellosis is controlled in the animal reservoirs, there is a corresponding and significant decline in the incidence in humans.

Key words: Brucellosis; zoonosis; research advancement

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