›› 2010, Vol. 37 ›› Issue (10): 39-42.

• 生理生化 • 上一篇    下一篇

山毛豆对小白鼠的亚慢性毒性试验研究

蔡小艳1, 赖志强1, 王士长2, 蒋建生2, 易显凤1, 韦锦益1, 梁永良1   

  1. (1.广西畜牧研究所, 南宁 530001;2.广西大学动物科学技术学院, 南宁 530003)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2010-10-20 发布日期:2010-10-20
  • 通讯作者: 赖志强

Sdudy on Subchronic Toxicity Test of Tephrosia canadida DC. on Mice

CAI Xiao-yan1, LAI Zhi-qiang1, WANG Shi-chang2, JIANG Jian-sheng 2, YI Xian-feng1 ,WEI Jin-yi1, LIANG Yong-liang1   

  1. (1.Guangxi Institutes of Animal Science, Nanning 530001,China;2.College of Animal Science and Technology of Guangxi University,Nanning 530003,China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2010-10-20 Published:2010-10-20
  • Contact: LAI Zhi-qiang

摘要: 为开发山毛豆(Tephrosia canadida DC.)作为蛋白质饲料资源,进行了山毛豆亚慢性毒性试验,即在饲粮中用山毛豆叶粉替代20%、40%和60%的基础日粮饲喂小白鼠,对各组小白鼠的采食、生长、脏器系数及组织切片等指标进行了测定和分析。结果表明:①试验期间,小白鼠活动正常,对照组和试验组小白鼠都没有死亡;②试验组小白鼠的各脏器无明显肉眼可见剖检病变;③试验组小白鼠的各脏器系数与对照组差异不显著(P>0.05);④40%和60%试验组小白鼠肝脏、肾脏的组织形态发生轻微变化,其他脏器均正常。研究结果表明,山毛豆草粉可安全用于动物饲料中。

关键词: 山毛豆; 亚慢性毒性试验; 采食量; 脏器系数; 组织切片

Abstract:

In order to explore Tephrosia canadida DC. as a new kind of protein forage resource, sub chronic toxicity test of diet with Tephrosia canadida DC. of mice was carried out. The diets containing different proportions of Tephrosia canadida DC. powder were fed to mice,the intake condition,growth condition,organ coefficient and tissue slice were measured and analyzed. The results showed that:① In the course of the test,the mice were normal and there wete no mice dead in the control or test groups;②There was no pathological change in viscera,after mice of the test groups were killed;③Organ coefficients of mice were no significant difference (P>0.05)between the control and test groups;④The liver and kidney tissue of mice in test group C(40%) and D(60%)changed slightly,while other viscera had no change.It indicated that Tephrosia canadida DC. could be safely used as animal forage.

Key words: Tephrosia canadida DC.; sub chronic toxicity test; intake; organ coefficient; tissue slice.

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