›› 2007, Vol. 34 ›› Issue (9): 50-52.

• 生物技术 • 上一篇    下一篇

猪β防御素-1的研究进展

孟虹艳1,2,李培锋1,朱建国2,华修国2,杨志彪2
  

  1. 1.内蒙古农业大学动物科学与医学学院,呼和浩特 010018;2 上海交通大学农业与生物学院,上海 200240
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2007-09-20 发布日期:2007-09-20

Advances in the Research of Porcine β Defensin-1

MENG Hong yan1,2,LI Peifeng1,ZHU Jianguo2,HUA Xiuguo2,YANG Zhibiao2
  

  1. 1.Inner Mongolia Agriculture University College of Animal Science and Animal Medicine, Huhhot 010018,China; 2.Shanghai Jiao Tong University College of Agriculture and Biology, Shanghai 200240,China
  • Received:1900-01-01 Revised:1900-01-01 Online:2007-09-20 Published:2007-09-20

摘要: 猪β防御素-1 (porcine β-defensin 1,PBD-1)是广泛分布于猪消化道、呼吸道、肝肾等多种组织细胞内的一类活性多肽,在猪防御系统中有着重要的作用,大量研究结果证明PBD-1具有独特的作用机制,几乎无耐药性, 已引起各国研究者的日益重视。目前对PBD-1科研工作在不断深入,可以相信PBD-1将在动物养殖、疾病预防和提高畜产品品质方面发挥重要作用。作者就PBD-1的分布、分子结构、抗菌作用机制和基因表达调控研究进展作一综述。

关键词: 猪β防御素-1; 抗菌肽; 研究进展

Abstract: PBD-1 is an antibacterial peptide that plays an important role in defense system of porcine. which have high expression in porcine respiratory and digestive tracts and also in liver, kidney and more tissue cells. lots of researches prove PBD-1 has distinctive function mechanism and hardly noendurance to pill. So more researchers of every country have pay attention increasingly to it. now the research work for PBD-1 is more deeply.PBD-1 plays a important role in animal breeding,illness prevention and progression of quality of livestock good. Here we report PBD-1’s research advancement on PBD-1 distribution,properties,molecular structure, mechanisms of antimicrobial activity and gene expression and regulation. 

Key words: PBD-1; antimicrobial peptide; research advancement

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