[1] BROWN E D,WRIGHT G D.Antibacterial drug disco-very in the resistance era[J].Nature,2016,529(7586):336-343. [2] RAO L L,LV L C,ZENG Z L,et al.Increasing prevalence of extended-spectrum cephalosporin-resistant Escherichia coli in food animals and the diversity of CTX-M genotypes during 2003-2012[J].Veterinary Microbiology,2014,172(3-4):534-541. [3] TIBERI S,ZUMLA A,MIGLIORI G B.Multidrug and extensively drug-resistant tuberculosis:Epidemiology,clinical features,management and treatment[J].Infectious Disease Clinics of North America,2019,33(4):1063-1085. [4] DA SILVA A C,RODRIGUES M X,SILVA N C C.Methicillin-resistant Staphylococcus aureus in food and the prevalence in Brazil:A review[J].Brazilian Journal of Microbiology,2020,51(1):347-356. [5] VAN BOECKEL T P,PIRES J,SILVESTER R,et al.Global trends in antimicrobial resistance in animals in low- and middle-income countries[J].Science,2019,365(6459):eaaw1944. [6] BAKKEREN E,HUISMAN J S,FATTINGER S A,et al.Salmonella persisters promote the spread of antibiotic resistance plasmids in the gut[J].Nature,2019,573(7773):276-280. [7] PIRES J,SIRIWARDENA T N,STACH M,et al. In vitro activity of the novel antimicrobial peptide dendrimer G3KL against multidrug-resistant acinetobac-terbaumannii and Pseudomonas aeruginosa[J].Antimi-crobial Agents and Chemotherapy,2015,59(12):7915-7918. [8] VERGIS J,MALIK S V S,PATHAK R,et al.Efficacy of indolicidin,cecropin A (1-7)-melittin (CAMA) and their combination against biofilm-forming multidrug-resistant enteroaggregative Escherichia coli[J].Probiotics and Antimicrobial Proteins 2020,12(2):705-715. [9] ALMATAR M,MAKKY E A,YAKICI G,et al.Antimicrobial peptides as an alternative to anti-tuberculosis drugs[J].Pharmacological Research,2018,128:288-305. [10] ZHENG Z,THARMALINGAM N,LIU Q,et al.Synergistic efficacy of Aedesaegyptiantimicrobial peptide cecropin A2 and tetracycline against Pseudomonas aeruginosa[J].Antimicrobial Agents and Chemotherapy,2017,61(7):e00686-17. [11] LIAN K Q,ZHANG M L,LIANG X L,et al.Identification and characteristics of a novel cecropin from the armyworm,Mythimna separata[J].BMC Microbiology,2020,20(1):233. [12] SHEN Z Q,WANG Y,SHEN Y B,et al.Early emergence of mcr-1 in Escherichia coli from food-producing animals[J].The Lancet Infectious Diseases,2016,16(3):293. [13] PEI Z H,BIAN L,ZHANG H,et al.Cloning,expression,and purification of a new antibacterial substance gene from Larvae of Muscadomestica (Diptera:Muscidae)[J].Journal of Insect Science,2014,14:253. [14] WANG L,ZHAO X Q,XIA X J,et al.Antimicrobial peptide JH-3 effectively kills Salmonella enterica serovar Typhimurium strain CVCC541 and reduces its pathogenicity in mice[J].Probiotics and Antimi-crobial Proteins,2019,11(4):1379-1390. [15] 钟亨任,谢志鹏,魏涵淇,等.抗菌肽Brevinin-GR23抗金黄色葡萄球菌作用机制的初步研究[J].海南大学学报(自然科学版),2018,36(4):360-367. ZHONG H R,XIE Z P,WEI H Q,et al.Mechanism of Brevinin-GR23 against Staphylococcus aureus[J].Natural Science Journal of Hainan University,2018,36(4):360-367.(in Chinese) [16] 王青,徐彦召,杨磊,等.一种广谱、低毒的抗菌肽类似物HJH-3的生物学活性和膜活性的测定[J].中国预防兽医学报,2019,41(8):800-806. WANG Q,XU Y Z,YANG L,et al.Determination of bioactivity and membrane activity of bovine antimicrobial peptide HJH-3[J].Chinese Journal of Preventive Veterinary Medicine,2019,41(8):800-806.(in Chinese) [17] HILCHIE A L,WUERTH K,HANCOCK R E.Immune modulation by multifaceted cationic host defense (antimicrobial) peptides[J].Nature Chemical Biology,2013,9(12):761-768. [18] LAI Y P,GALLO R L.AMPed up immunity:How antimicrobial peptides have multiple roles in immune defense[J].Trends in Immunology,2009,30(3):131-141. [19] MWANGI J,HAO X,LAI R,et al.Antimicrobial peptides:New hope in the war against multidrug resistance[J].Zoological Research,2019,40(6):488-505. [20] GUANI-GUERRA E,SANTOS-MENDOZA T,LUGO-REYES S O,et al.Antimicrobial peptides:General overview and clinical implications in human health and disease[J].Clinical Immunology,2010,135(1):1-11. [21] ZHANG Q H,XU Y Z,WANG Q,et al.Potential of novel antimicrobial peptide P3 from bovine erythrocytes and its analogs to disrupt bacterial membranes in vitro and display activity against drug-resistant bacteria in a mouse model[J].Antimicrobial Agents and Chemotherapy,2015,59(5):2835-2841. [22] WANG X M,TENG D,MAO R Y,et al.Combined systems approaches reveal a multistage mode of action of a marine antimicrobial peptide against pathogenic Escherichia coli and its protective effect against bacterial peritonitis and endotoxemia[J].Antimi-crobial Agents and Chemotherapy,2017,61(1):e01056-16. [23] DONG Z,LUO W J,ZHONG H R,et al.Molecular cloning and characterization of antimicrobial peptides from skin of Hylaranaguentheri[J].Acta Biochimica et Biophysica Sinica,2017,49(5):450-457. [24] LIU Y,SONG M R,DING S Y,et al.Discovery of linear low-cationic peptides to target methicillin-resistant Staphylococcus aureus in vivo[J].ACS Infectious Diseases,2019,5(1):123-130. |