基于高通量测序技术的山羊遗传多样性及其生产性状研究进展

doi:10.16431/j.cnki.1671-7236.2017.10.019

摘要/Abstract

摘要：

近年来，高通量测序技术的规模化应用及生物信息技术的普及，极大地推动了家畜基因组学的发展，实现了分子育种标记全基因组水平的快速、精准定位，为全基因组选择育种奠定了重要基础。数千年来的驯化和选择，形成了用途多样的山羊品种，如乳用、皮用、绒用及肉用等，为人类提供了丰富的生产和生活资料。国内外学者采用高通量测序技术对山羊的遗传多样性及生产性能的遗传机制进行了研究，以期找到与山羊种质特性相关的基因，从而为山羊的遗传改良提供新的标记。作者对近五年来基于高通量测序技术研究山羊的遗传多样性和产绒、产奶、繁殖等生产性状的研究进展进行了综述，以期为评估山羊优良种质特性和与生产性状相关的优异基因定位的工作提供参考。

关键词: 山羊; 生产性状; 基因组学; 转录组

Abstract:

Recently, the widespread use of high-throughput sequencing technology and the development of bioinformatics have been greatly contributed to the development of farm animal genomics. Whole genome-wide analysis can facilitate the fine mapping of the molecular markers related to the production traits quickly and accurately, thus providing an important theoretical basis for genome selection breeding. Several thousand years of domestication and artificial selection produce many modern goat breeds with high production of milk, fiber, and meat, which become abundant production and living materials for human populations. Researchers have studied the genetic diversity and molecular mechanisms of production traits in goats using high-throughput sequencing technology, in order to identify candidate genes related to the excellent germplasm reliable markers for genetic improvement. In this review, we summarized the five-year research progress on the genetic diversity and production traits of goats including fiber, milk production and reproduction traits, mainly based on high-throughput sequencing technology. This paper provides a reference for the evaluation of the excellent goat genetic resources and the investigation of production trait related genes.

Key words: goat; production traits; genomics; transcriptome

中图分类号:

S813.3

宋伸, 杨敏, 蒋琳, 马月辉. 基于高通量测序技术的山羊遗传多样性及其生产性状研究进展[J]. 《中国畜牧兽医》, 2017, 44(10): 2965-2972.

SONG Shen, YANG Min, JIANG Lin, MA Yue-hui. Research Progress on Goat Genetic Diversity and Production Traits Based on High-throughput Sequencing Technology[J]. , 2017, 44(10): 2965-2972.

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