《中国畜牧兽医》 ›› 2016, Vol. 43 ›› Issue (8): 2060-2065.doi: 10.16431/j.cnki.1671-7236.2016.08.019

• 生理生化 • 上一篇    下一篇

温度变化对家兔离体小肠平滑肌运动的影响

卡力比夏提·艾木拉江1, 周玉东2, 闫书平1, 哈力旦·阿合买提1, 赵红琼1   

  1. 1. 新疆农业大学动物医学学院, 乌鲁木齐 830052;
    2. 新疆生产建设兵团第七师畜牧兽医站, 奎屯 833200
  • 收稿日期:2016-01-06 出版日期:2016-08-20 发布日期:2016-08-23
  • 通讯作者: 赵红琼 E-mail:zhaohongqiong@sina.com
  • 作者简介:卡力比夏提·艾木拉江(1992-),男,新疆伊宁人,硕士,研究方向:生物活性物质功能,E-mail:18699166183@sina.cn
  • 基金资助:

    国家自然科学基金(31560684);国家科技支撑项目(2012BAD46B02);新疆农业大学大型仪器设备运用开发项目(sysblx016)

Effects of Temperature Changes on the Contractility of Isolated Small Intestinal Smooth Muscle in Rabbits

KALIBIXATI·Aimulajiang1, ZHOU Yu-dong2, YAN Shu-ping1, HALIDAN·Ahemaiti1, ZHAO Hong-qiong1   

  1. 1. College of Veterinary Medicine, Xinjiang Agricultural University, Urumqi 830052, China;
    2. Animal Husbandry and Veterinary Station, Xinjiang Production and Construction Corps Seventh Division of Animal Husbandry Bureau, Kuitun 833200, China
  • Received:2016-01-06 Online:2016-08-20 Published:2016-08-23

摘要:

为了探究温度变化对动物消化道平滑肌运动的影响,本试验用生物信号处理系统测定了浴槽不同温度(39→32℃、32→39℃、39→42℃和42→39℃)对家兔离体小肠各段(十二指肠、空肠、回肠)平滑肌运动的影响。结果显示,当温度在39和32℃之间变化时家兔离体十二指肠和空肠运动的收缩频率同温度变化呈正相关,而十二指肠收缩幅度和收缩张力同温度变化呈负相关,但回肠仅表现在收缩频率同温度变化呈正相关;当温度从39℃升高到42℃时,十二指肠的收缩频率、收缩幅度和收缩张力变化与温度在39和32℃之间变化情况相同,但是空肠和回肠的规律性较差;当温度从42℃高温降低到39℃时,3段离体小肠运动不能恢复到39℃时的运动状态,家兔小肠离体试验浴槽最适温度为37℃。本研究结果提示,在进行动物小肠离体试验时应注意浴槽温度对小肠运动的影响,同时本研究结果也为探究由于环境温度变化导致的动物胃肠运动异常的机理提供参考。

关键词: 家兔; 小肠; 平滑肌; 温度; 收缩频率; 收缩幅度; 收缩张力

Abstract:

In order to explore the influence of temperature changes on animal digestive tract smooth muscle,the contractility of isolated rabbit small intestine (duodenum,jejunum and ileum) were measured at different temperatures (39→32℃,32→39℃,39→42℃ and 42→39℃) using the biological signal processing system.The results showed that the contraction frequency of duodenum and jejunum was positively correlated with temperature changes between 39 and 32℃,while the amplitude and tension of duodenum were negatively correlated with temperature changes.Only the contraction frequency of ileum was positively correlated with temperature changes between 39 and 32℃.Changes of frequency,amplitude and tension of duodenum between 39 and 42℃ were similar with those changes between 39 and 32℃.However,the contraction of jejunum and ileum was irregular.When the temperature was decreased from 42 to 39℃,the contraction of small intestine could not return to the condition in 39℃.The results suggested that the optimal bath temperature was 37℃ in contraction test of rabbit small intestine in vitro,and the present results could be referenced to explore the disorder of gastrointestinal movement due to the change of environment temperature in animals.

Key words: rabbit; small intestine; smooth muscle; temperature; contraction frequency; contraction amplitude; contraction tension

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