›› 2016, Vol. 43 ›› Issue (1): 242-247.doi: 10.16431/j.cnki.1671-7236.2016.01.038

• 疾病防治 • 上一篇    下一篇

动物抗寄生虫药物作用机理研究进展

张吉丽, 李冰, 周绪正, 张继瑜   

  1. 中国农业科学院兰州畜牧与兽药研究所, 农业部兽药创制重点实验室, 兰州 730050
  • 收稿日期:2015-06-16 出版日期:2016-01-20 发布日期:2016-01-23
  • 通讯作者: 张继瑜 E-mail:infzjy@sina.com
  • 作者简介:张吉丽(1992-),女,黑龙江大庆人,硕士,研究方向:动物抗寄生虫药,E-mail:zhangjlzjl@qq.com
  • 基金资助:
    国家现代农业产业技术体系专项(CARS-38);"十二五"国家科技支撑计划项目(2015BAD1101)

Research Progress on Action Mechanism of Animal Anti-parasitical Drugs

ZHANG Ji-li, LI Bing, ZHOU Xu-zheng, ZHANG Ji-yu   

  1. Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, CAAS, Lanzhou 730050, China
  • Received:2015-06-16 Online:2016-01-20 Published:2016-01-23

摘要: 动物抗寄生虫药物主要用于防制动物寄生虫病,是保障畜牧业健康发展和公共卫生安全的有效手段。抗寄生虫药物的药效建立在药物分子与寄生虫或动物机体不同靶组织、靶细胞间相互作用的基础上。由于抗寄生虫药物种类多样,抗寄生虫机理复杂。随着新抗寄生虫药物的开发和科学研究的深入,尤其是化学合成和生物制药技术的发展,抗寄生虫药物的品种和数量都在不断的增加,新的药物结构和作用靶标不断发现,作用机理研究也不断深入。作者主要对抗寄生虫药物的作用机理研究进展进行综述。

关键词: 动物; 抗寄生虫药物; 机理

Abstract: Animal anti-parasitical drugs are mainly used to prevent and control animal parasitosis, and also an effective way to protect the healthy development of animal husbandry and public health security.The efficacy of anti-parasitical drugs depends on the interaction between drug molecular and different target tissues and target cells of parasite or animal.Because of the variety of anti-parasitical drugs, the anti-parasitical mechanisms are complex.With the development of new anti-parasitical drugs and the depth of scientific research, especially the development of chemical synthesis and biological pharmaceutical technology, the variety and quantity of anti-parasitical drugs constantly increase.With the discovery of new drug structure and its action target, the study on the mechanism is constantly deep.The author mainly summarized the research progress on action mechanism of anti-parasitical drugs.

Key words: animal; anti-parasitical drugs; mechanism

中图分类号: