›› 2018, Vol. 45 ›› Issue (6): 1683-1691.doi: 10.16431/j.cnki.1671-7236.2018.06.033

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Study on Anticoccidial Efficacy of Artemisia annua Powder

NIU Biao1, QIN Wenwen1, GUO Wenzhu1, ZHANG Pujun2, MA Liping2, HUANG Xin1, LIU Yu1, LIANG Jianping1   

  1. 1. Key Laboratory of New Animal Drug Project, Gansu Province, Key Laboratory of Veterinary Pharmaceutics Discovery, Ministry of Agricultural, Lanzhou Institute of Husbandry and Pharmaceutical Sciences of CAAS, Lanzhou 730050, China;
    2. Animal Health Inspection Institute of Agriculture and Animal Husbandry Bureau of Helinger, Helinger 011500, China
  • Received:2017-12-04 Online:2018-06-20 Published:2018-06-15

Abstract:

In order to investigate the control effect of Artemisia annua powders on chicken coccidian,90 healthy yellow feather broilers were selected and divided into 6 groups.Except the blank control group,other chickens were infected with Eimeria tenella (E.tenella),with 6×104 sporulated oocysts,and each test group began to use drugs on the day before the vaccination,until to the end of the test.By recording the indexs of each test group,including their macroscopical lesion,histopathological examination,relative weight-growth rate,lesion scores of pathological changes of cecum,lesion scores of bloody stool,the number of oocysts (OPG),per gram of feces,oocyst score and anticoccidial index (ACI),the thesis made attempts to evaluate anticoccidia effects.The results revealed that the ACI of blank control group,infection control group,drug control group and low,middle and high dose groups of Artemisia annua powders were 200.00,72.23,157.19,82.89,125.32 and 137.06,respectively.Compared with infection control group,the macroscopical lesion,histopathological examination of drug control group and drug supplied groups of Artemisia annua powders were relieved.Artemisia annua powders could reduce sick chicken's cecum swelling and bleeding and other symptoms,and they were in much better spirits than infection control group.Compared with the infection control group,the average weight gain of each drug supply group were all increased,and their cecal lesion scores,oocyst score and bloody stools decreased.The results showed that Artemisia annua powders could alleviate pathological symptoms and tissue lesions infected by Eimeria tenella of chicken cecum,and reduce the amount of feces in the oocysts.The higher the concentration of administration,the better the anticoccidial effect,which was dose-dependent.

Key words: Artemisia annua powder; Eimeria tenella; anti-chicken coccidian; anti-coccidia index

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