复合益生菌对早期断奶仔猪生长性能和免疫水平的影响

doi:10.16431/j.cnki.1671-7236.2018.06.012

Abstract

Abstract:

In order to explore the effect of compound probiotic (Saccharomyces cerevisiae + Bacillus subtilis) on immunity level of early weaned piglets,80 weaned piglets (Duroc pig×Landrace pig×Yorkshine pig) were equally divided into four groups and 20 pigs per group.The pigs in groups Ⅰ,Ⅱ and Ⅲ were fed basal diet with 0.10%,0.20% and 0.30% compound probiotic,respectively,others in control group were fed with basal diet,so as to evaluate the growth performance,blood biochemistry,serum cytokines and intestinal mucosal SIgA levels.The results showed that the final body weight of groups Ⅱ and Ⅲ were extremely significantly higher than group Ⅰ and control group (P<0.01).The average daily feed intake of group Ⅲ was the highest in the experimental groups,which was higher than groups Ⅰ,Ⅱ and control group (P<0.05).The diarrhea rates in control group and group Ⅱ were extremely significantly higher than groups Ⅰ and Ⅲ (P<0.01).The content of lactic dehydrogenase (LDH),alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the experimental group were higher than that of control group,and the total protein (TP) was lower than that of control group (P>0.05).The content of serum urea nitrogen (BUN) in the experimental groups were significantly higher than that of control group (P<0.05),and the content of aspertate transaminase (AST) in groups Ⅱ and Ⅲ were significantly higher than that of group Ⅰ and control group (P<0.05).At 0 day,the level of IL-6,IL-1β and TNF-α in the experimental groups were not significantly different from that of control group (P>0.05).At 20 days,the level of IL-6 in groups Ⅱ and Ⅲ were extremely significantly higher than that of group Ⅰ and control group (P<0.01),the levels of IL-1β and TNF-α were no significant difference compared with control group (P>0.05).At 40 days,the level of IL-1β in experimental groups were higher than that of control group (P>0.05),the level of IL-6 and TNF-α were extremely significantly higher than that of control group (P<0.01).The level of SIgA of jejunum mucosa,duodenum and ileum mucosa in experimental groups were extremely significantly or significantly higher than that of control group (P<0.01; P<0.05),the level of SIgA of cecum mucosa was lower than control group (P>0.05).It showed that different contents of compound probiotics (Saccharomyces cerevisiae + Bacillus subtilis) could effectively improve the growth performance of weaned piglets,alleviate the stress response and enhance the immune function.

Key words: compound probiotics; growth performance; immunity levels; weaned piglets

CLC Number:

S816.71

ZHU Yongcai, HU Xingyi, ZHANG Shuangxiang, ZHOU Bijun, CHEN Guoquan, CHEN Guang, WANG Kaigong, WEN Ming, CHENG Zhentao, WEN Guilan, ZHANG Hai, FENG Xufang. Effects of Compound Probiotics on Growth Performance and Immune Levels of Early Weaned Pigs[J]. , 2018, 45(6): 1518-1525.

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Effects of Compound Probiotics on Growth Performance and Immune Levels of Early Weaned Pigs

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