同源异型框基因Prrx功能的研究进展

doi:10.16431/j.cnki.1671-7236.2017.02.042

Abstract

Abstract:

The homeobox (HoX) gene that controls cell differentiation and morphological development is an important gene having highly genetic level. These genes highly express in the embryonic period and affect the embryonic development and differentiation and control the development of body structure and organs. The homeobox gene Prrx includes three types, Prrx1, Prrx2 and Prrx3, this family gene plays an important role in the development of cleft palate, jaw, extremities, tibia and fibula in human and mouse, and is also closely related to the development of the brain, spinal cord, nerve, heart and other organs. The Prrx1 and Prrx2 are mainly involved in the development of bone and cardiovascular system in embryo, such as limb, craniofacial, cartilage and arteries, and Prrx3 is mainly involved in the development of embryonic cartilage, bone, brain, spinal cord and so on. This paper reviewed the functions of Prrx gene, so as to provide certain references for research on the gene functions and prevention and control of related diseases.

Key words: homeobox; Prrx gene; growth and development

CLC Number:

XU Xiao-tong, ZHANG Xin, DU Juan, YANG Xiao-nong. Research Progress on Functions of Homeobox Gene Prrx[J]. , 2017, 44(2): 607-612.

References

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Research Progress on Functions of Homeobox Gene Prrx

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