绵羊骨骼肌生长发育调控基因研究进展

doi:10.16431/j.cnki.1671-7236.2019.05.021

Abstract

Abstract:

Skeletal muscle development is a complex process involving the formation and proliferation of muscle cells,the formation of muscle ducts and muscle fibers,and the final maturation process.The growth and development of skeletal muscle directly affects the production performance in sheep.With the development of sequencing technology,more and more people are trying to elucidate the systematic regulatory network of skeletal muscle development from the genetic level,and explore the molecular markers related to the important functional traits such as meat quality and meat production performance.Cell enhancement factor 2 (MEF2) is a conserved and functional transcription factor that controls the expression of muscle genes and plays a role in regulating muscle generation,neural development and differentiation.Myogenic differentiation (MyoD) gene family regulates the differentiation of myocytes and the maturation of skeletal muscle system.In order to further understand the function of sheep skeletal muscle and its growth and development regulatory genes,starting from the structural features of skeletal muscle,this paper focuses on the structure and function of MEF2 and MyoD genes family and the regulation of non-coding gene on gene expression in skeletal muscle.

Key words: sheep; skeletal muscle; MEF2 gene; MyoD gene; growth and development

CLC Number:

S813.3

SUN Yanyong, FU Shaoyin, QI Yunxia, HE Xiaolong, SUN Dexin, FANG Qinyuan, CHEN Xin, LIU Yongbin, ZHANG Wenguang. Research Advances on Regulation Genes of Growth and Development of Skeletal Muscle in Sheep[J]. , 2019, 46(5): 1429-1438.

References

[1] CHARGE S B,RUDNICKI M A.Cellular and molecular regulation of muscle regeneration[J].Physiological Reviews,2004,84(1):209-238.
[2] YIN H,LI D,WANG Y,et al.Myogenic regulatory factor (MRF) expression is affcted by exercise in postnatal chicken skeletal muscles[J].Gene,2015,561(2):292-299.
[3] EDMONDSON D G,LYONS G E,MARTIN J F,et al.Mef2 gene-expression marks the cardiac and skeletal-muscle lineages during mouse embryogenesis[J].Development,1994,120(5):1251-1263.
[4] YOKOYAMA S,ASAHARA H.The myogenic transcriptional network[J].Cell and Molecular Life Sciences,2011,68(11):1843-1849.
[5] GIUDICE J,LOEHR J A,RODNEY G G,et al.Alternative splicing of four trafficking genes regulates myofiber structure and skeletal muscle physiology[J].Cell Reports,2016,17(8):1923-1933.
[6] GONG C,LI Z,RAMANUJAN K,et al.A long non-coding RNA,lncMyoD,regulates skeletal muscle differentiation by blocking IMP2-mediated mRNA translation[J].Developmental Cell,2015,34(2):181-191.
[7] HORAK M,NOVAK J,BIENERTOVA-VASKU J.Muscle-specific microRNAs in skeletal muscle development[J].Developmental Biology,2016,410(1):1-13.
[8] LIEBER R L.Skeletal muscle structure and function,& plastictity:The physiological basis of rehabilitation[M].Lippincott Williams & Wikins,2002.
[9] ZHAO X,MO D,LI A,et al.Comparative analyses by sequencing of transcriptomes during skeletal muscle development between pig breeds differing in muscle growth rate and fatness[J].PLoS One,2011,6(5):e19774.
[10] XU Y,QIAN H,FANG X,et al.Differential proteome and transcriptome analysis of porcine skeletal muscle during development[J].Journal of Proteomics,2012,75(7):2093-2108.
[11] BUCKINGHAN M,RELAIX F.The role of pax genes in the development of tissues and organs:pax3 and pax7 regulate muscle progenitor cell functions[J].Annual Review of Cell Developmental Biology,2007,23(23):645-673.
[12] CHOI Y M,NAM K W,CHOE J H,et al.Growth,carcass,fiber type,and meat quality characteristics in Large White pigs with different live weights[J].Livestock Science,2013,155(1):123-129.
[13] PETER J B,BAMARD R J,EDGERTON V R.Metabolic profiles of three fiber types of skeletal muscle in guinea pigs and rabbits[J].Biochemistry,1972,11(14):2627-2633.
[14] AUSONI S,GORZA L,SCHIAFFINO S,et al.Eepression of myosin heavy chain isoforms in stimulated fast and slow rat muscles[J].Journal of Neuroscience the Official Journal of the Society for Neuroscience,1990,10(1):153-160.
[15] MICHAEL V,TAYLOR,SIMON M,et al.Mef2 and the skeletal muscle differentiation program[J].Seminars in Cell & Developmental Biology,2017,72:33-44.
[16] SCHIAFFINO S,SANDRI M,MURGIA M.Activity-dependent signaling pathways controlling muscle diversity and plasticity[J].Pgysiology,2007,22(4):269-278.
[17] HEMMINGS K M,DANIEL Z C T R,BUTTERY P J,et al.Differential effects of short-term β agonist and growth hormone treatments on expression of myosin heavy chain ⅡB and associated metabolic genes in sheep muscle[J].Animal,2015,9(2):285-294.
[18] BLACK B L,OLSON E N.Transcriptional control of muscle development by myocyte enhancer factor-2(MEF2) proteins[J].Annual Review of Cell and Developmental Biology,1998,14(1):167-196.
[19] DESJARDINS C A,NAYA F J.The function of the MEF2 family og transcription factors in cardiac development,cardiogenomics,and direct reprogramming[J].Journal of Cardiovascular Development and Disease,2016,3(3):26.
[20] MEIERHANS D,SIEBER M,ALLEMANN R K.High affinity binding of MER-2C correlates with DNA bending[J].Necleic Acids Research,1997,25(22):4537-4544.
[21] WU Y,DEY R,HAN A,et al.Structure of the MADS-box/MEF2 domain of MEF2A bound to DNA and its implication for myocardin recruitment[J].Journal of Molecular Biology,2010,397(2):520-533.
[22] POTTHOFF M J,OLSON E N.MEF2:A central regulator of diverse developmental programs[J].Development,2007,134(23):4131-4140.
[23] 王乐.FoxO1与其调控肌纤维类型相关的研究及对羊肌肉的影响[M].呼和浩特:内蒙古农业大学,2016. WANG L.The study of FoxO1 and gene of muscle fiber specification and its effect on meat quality in sheep[D].Hohhot:Inner Mongolia Agricultural University,2016.(in Chinese)
[24] MOLKENTIN J D,BLACK B L,MARTIN J F,et al.Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH protein[J].Cell,1955,83(7):1125-1136.
[25] KWON A T,CHOU A Y,ARENILLAS D J,et al.Validation of skeletal muscle cis-regulatory module presictions reveals nuceotide compositon bias in functional enhancers[J].PLoS Computational Biology,2011,7(12):e1002256.
[26] BRENNAN T J,CHAKRABORTY T,OLSON E N.Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis[J].Proceedings of the National Academy of Sciences of the United States of America,1991,88(13):5675-5679.
[27] ORNATSKY O J,ANDREUCCI J J,MCDERMOTT J C.A dominat-negative form of transcription factor MEF2 inhibits myogenesis[J].The Journal of Biological Chemistry,1997,272(52):33271-33278.
[28] SNYDER C M,RICE A L,ESTRELLA N L,et al.MEF2A regulates the Gtl2-Dio3 mucroRNA mega-cluster to modulate WNT signaling in skeletal muscle regeneration[J].Development,2013,140(1):31-42.
[29] 马晓萌.乌珠穆沁绵羊MEF2B、RIPK2、CAMKMT基因多态性与生长性状的关联分析[D].北京:中国农业科学院,2016. MA X M.Single nucleotide polymorphism of MEF2B,RIPK2,CAMKMT genes and associations with growth traits in Ujumqin sheep[D].Beijing:Chinese Academy of Agricultural Sciences,2016.(in Chinese)
[30] 张春兰.小尾寒羊和杜泊羊臂二头肌转录组及肌球蛋白轻链基因家族结构特征分析[D].泰安:山东农业大学,2014. ZHANG C L.Transcriptome analysis of Small-tailed Han sheep and Dorper's biceps brachii and structure characteristics of myosin light chain gene families[D].Tai'an:Shandong Agricultural University,2014.(in Chinese)
[31] ZHANG S Z,XU Y,XIE H Q,et al.The possible role of myosin light chain in myoblast proliferation[J].Biological Research,2009,42(1):121-132.
[32] 张莉,刘佳森,徐凌洋,等.绵羊体重性状全基因组关联分析[J].中国畜牧兽医,2014,41(2):194-203. ZHANG L,LIU J S,XU L Y,et al.Genome-wide association studies for body weight traits in sheep[J].China Animal Husbandry & Veterinary Medicine,2014,41(2):194-203.(in Chinese)
[33] SUN L M,BAI M,XIANG L J,et al.Comparative transcriptome profiling of longissimus muscle tisses from Qianhua Mutton Merino and Small-tail Han sheep[J].Scientific Reports,2016,6:33586.
[34] COMAI G,TAJBAKHSH S.Molecular and cellular regulation of skeletal myogenesis[J].Current Topics in Developmental Biology,2014,110:1-73.
[35] DUCHOSSOY L K,MOREL B G,GOMERS D,et al.Mrf4 determines skeletal muscle identity in Myf5:MyoD double-mutant mice[J].Nature,2004,431(7007):466-471.
[36] DAVIS R L,WEINTRAUB H,LASSAR A B.Expression of a single transfected cDNA converts fibroblasts to myoblasts[J].Cell,1987,51(6):987-1000.
[37] 任霆,郭月英,张静,等.MRFs基因家族对肉品质的影响[J].食品工业科技,2014,16:363-366. REN T,GUO Y Y,ZHANG J,et al.Effect of myogenic regulatory factors (MRFs) to meat quality[J].Science and Technology of Food Industry,2014,16:363-366.(in Chinese)
[38] NAYA F J,OLSON E.MEF2:A transcriptional target for signaling pathways controlling skeletal muscle growth and differentiation[J].Current Opinion in Cell Biology,1999,11(6):683-688.
[39] BERKES C A,BERGSTROM D A,PENN B H,et al.Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic prtential[J].Molecular Cell,2004,14(4):465-477.
[40] BUCKINGHAM M,RIGBY P W.Gene regulatory networks and transcriptional mechanisms that control myogenesis[J].Developmental Cell,2014,28(3):225-238.
[41] OHKAWA Y,MARFELLA C G,IMBALZANO A N.Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1[J].EMBO Journal,2014,25(3):490-501.
[42] IWAFUCHI-DOI M,ZARET K S.Cell fate control by pioneer transcription factors[J].Development,2016,143(11):1833-1837.
[43] WAPONSKI O L,VIERBUCHEN T,QU K,et al.Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons[J].Cell,2013,155(3):621-635.
[44] BUCKINGHAM M,VINCENT S D.Distinct and dynamic myogenic populations in the vertebrate embryo[J].Current Opinion Genetics & Development,2009,19(5):444-453.
[45] DEDKOV E I,KOSTROMINOVA T Y,BORISOV A B,et al.MyoD and myogenin protein expression in skeletal muscles of senile rats[J].Cell Tissue Research,2003,311(3):401-416.
[46] 项露颉.生肌决定因子MyoD在不同品种肉羊肌肉中表达差异的研究[D].长春:吉林农业大学,2016. XIANG L J.The expression of MyoD gene in the muscle tissue of different mutton sheep[D].Changchun:Jilin Agricultural University,2016.(in Chinese)
[47] PENAGARICANO F,WANG X,ROSA G J,et al.Maternal nutrition induces gene expression changes in fetal muscle and adipose tissues in sheep[J].BMC Genomics,2014,15:1034.
[48] REHFEKDT C,STABENOW B,PFUHL R,et al.Effects of limited and excess protein intakes of pregnant gilts on carcass quality and cellular properties of skeletal muscle and subcutaneous adipose tissue in fattening pigs[J]. Journal of Animal Science,2012,90(1):184-196.
[49] RADUNZ A E,FLUHARTY F L,ZERBY H N,et al.Winter-feeding systems for gestating sheep I.Effects on pre- and postpartum ewe performance and lamb progeny preweaning performance[J].Journal of Animal Science,2011,89(2):467-477.
[50] YAN L,LUO H,GAO X,et al.Vascular endothelial growth factor-induced expression of its receptors and activation of the MAPK signaling pathway during ovine oocyte maturation in vitro[J].Theriogenology,2012,78(6):1350-1360.
[51] MA L,BAJIC V B,ZHANG Z.On the classification of long non-coding RNAs[J].RNA Biology,2013,10(6):925-933.
[52] SUN X,LI M,SUN Y,et al.The developmental transcriptome sequencing of bovine skeletal muscle reveals a long noncoding RNA,lncMD,promotes muscle differentiation by sponging miR-125b[J].Acta Biochimica et Biophysica Sinica,2016,1863(11):2835-2845.
[53] CESANA M,CACCHIARELLI D,LEGNINI I,et al.A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous[J].RNA Cells,2011,147(2):358-369.
[54] WANG L,ZHAO Y,BAO X,et al.lncRNA dum interacts with dnmts to regulate DPPA2 expression during myogenic differentiation and muscle regeneration[J]. Cell Research,2015,25(3):335-350.
[55] SAKAKIBARA I,SANTOLINI M,FERRY A,et al.Six homeoproteins and a lincRNA at the fast myhlocus lock fast myofiber terminal phenotype[J].Plos Genetics,2014,10(5):e1004386.
[56] NELSON B R,MAKAREWICH C A,ANDERSON D M,et al.A peptide encoded by a transcript annotated as long noncodingRNA enhances serca activity in muscle[J].Science,2016,351(6270):271-275.
[57] MATSUMOTO A,PASUT A,MATSUMOTO M,et al.MTORC1 and muscle regeneration are regulated by thelinc00961-encoded spar polypeptide[J].Nature,2016,541(7636):228-232.
[58] YU X,ZHANG Y,LI T,et al.Long non-coding RNA Linc-RAM enhances myogenic differentiation by interacting with MyoD[J].Nature Communications,2017,8:14016.
[59] HITACHI K,TSUCHIDA K.Myostatin-deficiency in mice increases global gene expression at the Dlk1-Dio3 locus in the skeletal muscle[J].Oncotarget,2017,8(4):5943-5953.
[60] LI C Y,LI X Y,LIU Z J,et al.Identification and characterization of long non-coding RNA in prenatal and postnatal skeletal muscle of sheep[J].Genomics,2019,111(2):133-141.
[61] BRACK A S,CONBOY M J,ROY S,et al.Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis[J].Science,2007,317(5839):807-810.
[62] GLASS D J.Signalling pathways that mediate skeletal muscle hypertrophy and atrophy[J].Nature Cell Biology,2003,5(2):87-90.
[63] MA J,FILL M,KNUDSON C M,et al.Ryanodine receptor of skeletal muscle is a gap junction-type channel[J].Science,1988,242(4875):99-102.
[64] CLEMENT K,VIGUERIE N,DIEHN M,et al. In vivo regulation of human skeletal muscle gene expression by thyroid hormone[J].Genome Research,2002,12(2):281-291.
[65] SANGER H L,KLOTZ G,RIESNER D,et al.Viroids are single-stranded covalently closed circularRNA molecules existing as highly base-paired rod-like structures[J].Proceedings of the National Academy of Sciences of the United States of America,1976,73(11):3852-3856.
[66] ABDELMOHSEN K,PANDA A C,DE S,et al.circularRNAs in monkey muscle:Age-dependent changes[J].Aging,2015,7(11):903-910.
[67] YANG O F H,NIE Q,ZHANG X.P3052 characterization of circular RNAs in relation to embryonic muscle development in chicken[J].Journal of Animal Science,2016,94:79.
[68] SUN J,XIE M,HUANG Z,et al.Integrated analysis of non-coding RNA andmRNA expression profles of 2 pig breeds differing in muscle traits[J].Journal of Animal Science,2017,95:1092-1103.
[69] LI C Y,LI X Y,YAO Y,et al.Genome-wide analysis of circular RNAs in prenatal and postnatal muscle of sheep[J].Oncotarget,2017,8(57):97165-97177.
[70] BARTEL D P.microRNAs:Target recognition and regulatory functions[J].Cell,2009,136(2):215-233.
[71] INUI M,MARTELLO G,PICCOLO S.microRNA control of signal transduction[J].Nature Reviews Molecular Cell Biology,2010,11(4):252-263.
[72] ELIA L,CONTU R,QUINTACALLE M,et al.Reciprocal regulation of microRNA-1 and insulin-like growth factor-1 signal transduction cascade in cardiac and skeletal muscle in physiological and pathological conditions[J].Circulation,2009,120(23):2377-2385.
[73] CHEN J F,TAO Y,LI J,et al.microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7[J].Journal of Cell Biology,2010,190:867-879.
[74] GE Y,SUN Y,CHEN J.IGF-Ⅱ is regulated by microRNA-125b in skeletal myogenesis[J].Journal of Cell Biology,2011,192(1):69-81.
[75] ROBERTS T C,BLOMBERG K E M,MCCLOREY G,et al.Expression analysis in multiple muscle groups and serum reveals complexity in the microRNA transcriptome of the mdx mouse with implications for therapy[J].Molecular Therapy Nucleic Acids,2012,1(8):e39.
[76] MIAO X Y,LUO Q M,QIN X Y.Genome-wide analysis reveals the differentiak regulations of mRNAs and miRNAs in Dorset and Small-tail Han sheep muscles[J].Gene,2015,562(2):188-196.
[77] VELLOSO C.Regulation of muscle mass by growth hormone and IGF-Ⅰ[J].British Journal of Pharmacology,2008,154(3):557-568.
[78] SJOGREN K,LEUNG K C,KAPLAN W,et al.Growth hormone regulation of metabolic gene expression in muscle:A microarray study in hypopituitary men[J].American Journal of Physiology-Endocrinology and Metabolism,2007,293(1):E364-E371.
[79] WANG L,FENG Z,WANG X,et al.DEGseq:An R package for identifying differentially expressed genes from RNA-Seq data[J].Bioinformatics,2010,26(1):136-138.
[80] STEPHANE B,CHRISTELLEH A,CHRISTOPHE P,et al.Muscle transcriptome analysis reveals molecular pathways and biomarkers involved in extreme ultimate pH and meat defect occurrence in chicken[J].Scientific Reports,2017,7(1):6447.

Research Advances on Regulation Genes of Growth and Development of Skeletal Muscle in Sheep

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	WANG Saiqiao, ZHAO Lu, ZHAI Zhenhan, ZHANG Binglei, JIA Wanhang, WANG Yuqin. Tissue Expression and Bioinformatics Analysis of miR-449a/b Precursor Sequences in Sheep [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(6): 2175-2184.
[2]	YANG Guitao, MA Jideng, LI Xuewei, GE Liangpeng, ZHANG Jinwei. Research Advance on Regulation of Skeletal Muscle Physiology Function by Short Chain Fatty Acids [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(6): 2286-2295.
[3]	LIU Jinyu, ZHANG Yang, MA Xumei, ZHOU Qian, ZHOU Yang, ZHANG Chunxiang, SHI Lei, REN Youshe. Effects of Glutathione on Cryopreservation of Sheep Semen [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(6): 2388-2394.
[4]	WU Zhijuan, CHAI Zhixin, WANG Jikun, WANG Jiabo, ZHONG Jincheng, XIN Jinwei. Expression Analysis of Specific Matrix Metalloproteinases and Functionally Related Genes of Skeletal Muscles in Yak [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 1774-1784.
[5]	ZHANG Huaqiang, WANG Pinsheng, LI Xiao, WEI Panpeng, YAN Lingmin, JIANG Bingbing, WANG Zhaogui, WANG Xuefang, ZENG Huanqing, FAN Yi, GAO Zhenglong, WANG Xuebing. Effects of Fermented Hybrid Broussonetia papyrifera on Growth Performance, Meat Quality,Digestive Enzyme Activity and Intestinal Flora Structure of Hu Sheep [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 1876-1887.
[6]	ZHAO Qianming, QI Meng, XU Zeli, GONG Pihong, LU Chenyang, PEI Zhiyang, JIAN Fuchun, WANG Jiandong, JING Bo, NING Changsheng. Investigation of Intestinal Parasites Occurrence in Sheep and Environmental Contamination in Large-scale Housing Farms [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 2156-2165.
[7]	CUI Shuang, Wurlig, Alder, XIAO Min, WANG Jianqiu, GONG Jian. Effects of Yeast Selenium Supplementation on Gastrointestinal Microflora in Sheep Under Grazing Conditions [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(3): 952-965.
[8]	ZHEN Zhen, WANG Mei, WANG Yimin, HU Debao, ZHANG Linlin, LI Xin, GUO Yiwen, GUO Hong, DING Xiangbin. Effect of RNA Methylation Transfer Enzyme METTL3 on the Proliferation and Myogenic Differentiation of Bovine Skeletal Muscle Satellite Cells [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(3): 1025-1036.
[9]	ZHANG Yongjie, SUI Zhiyuan, ZHANG Zhishuai, WANG Chenguang, LI Xiaojun, XING Feng. Cloning and Bioinformatics Analysis of NPTX1 Gene and Its Tissues Expression at Puberty in Dolang Sheep [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(3): 1048-1058.
[10]	ZHANG Mingliang, ZHANG Hailong, MA Shipeng, WANG Cailian, LANG Xia. Effects of Zanthoxylum bungeanum Essential Oil on Production Performance and Gastrointestinal Tissue Structure of Small-tail Han Sheep [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 556-563.
[11]	LI Chenglan, GUO Tingting, YUE Yaojing. Research Advances on Genomic Selection and Its Application in Sheep Breeding [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 616-625.
[12]	QIN Zhiyun, JIANG Huaizhi. An Overview of Research on Skin Hair Follicle Development and Regulatory Mechanism in Sheep During the Fetal Period [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(2): 638-646.
[13]	AN Xiaopeng, LIU Nan, HU Zhengjiamei, HU Jincao, XU Xiaolong, ZHANG Lei, SONG Yuxuan. Comparative Analysis of Lactation Performance of East Friesen Sheep, Hu Sheep and East Friesen-Hu Hybrid Sheep [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(1): 238-245.
[14]	TAN Haoyun, LIU Qian, HU Debao, ZHANG Linlin, LI Xin, DING Xiangbin, GUO Hong, GUO Yiwen. Effects of Interference lnc721 on Proliferation and Differentiation of Bovine Skeletal Muscle Satellite Cells [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3292-3300.
[15]	WEI Jia, BAI Qin, LUO Xiaolin, GUAN Jiuqiang, AN Tianwu, ZHAO Hongwen, TAN Wu, LI Huade, XIE Rongqing, SHA Quan, JIANG Mingfeng, ZHANG Xiangfei. Effects of Different Weaning Strategies on Growth, Serum Biochemical Indexes and Antioxidant Capacity of Yak Calves [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3400-3410.