不同月龄马身猪和大白猪血清生长激素及其受体的变化规律

doi:10.16431/j.cnki.1671-7236.2016.10.021

Abstract

Abstract:

The purpose of this study was to understand the change trend of growth hormone (GH) and growth hormone receptor (GHR) in serum of Mashen and Large White pigs during the period from 0 to 6 months of age,and to analyze the influence of GH and GHR on growth rate.The method of ELISA was used to detect the concentration of GH and GHR in serum of Mashen and Large White pigs from 0 to 6 months of age.The results showed that the variation trends of GH in Mashen pig was roughly the same as in Large White pig,the GH concentration was increased with age increasing after birth and reached the peaks at 4 and 5 months of age for Mashen and Large White pigs,respectively,and then decreased gradually.The serum GH concentration in Mashen pig was a little greater than that in Large White pig at 3 and 4 months of age,on the contrary,the serum GH concentration in Large White pig was greater than that in Mashen pig at other months.During the period from 0 to 6 months of age,the difference of GHR concentration in serum was not significant in Mashen pig (P>0.05).In Large White pig,the serum GHR concentration at 1 month of age was lowest,and was significantly lower than that at 4 and 6 months of age (P<0.01;P<0.05).During the period of 0 to 2 months of age,the GHR concentration in Mashen pig was greater than that in Large White pig,but the difference was extremely significant only at 1 month of age (P<0.01).Conversely,the serum GHR concentration in Large White pig was greater than those in Mashen pig during the period from 3 to 6 month of age,there was significant difference at 4 and 6 months of age (P<0.05),and there was extremely significant at 5 months of age(P<0.01).The concentration of GH and GHR in serum was related to the developmental stages and genetic background of pig,and its change trend was in accordance with the trend of growth rate.

Key words: pig; GH; GHR; change trend; ELISA

CLC Number:

S828.2

SHI Jian-zhong, LIU Yi, WANG Ze-yi, SHEN Nan, ZHANG Ning-fang, CHENG Zhi-min, GAO Peng-fei, GUO Xiao-hong, LI Bu-gao, CAO Guo-qing. Study on the Change Trend of Growth Hormone (GH) and Growth Hormone Receptor (GHR) in Serum at Different Months in Mashen and Large White Pigs[J]. , 2016, 43(10): 2655-2660.

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Study on the Change Trend of Growth Hormone (GH) and Growth Hormone Receptor (GHR) in Serum at Different Months in Mashen and Large White Pigs

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