畜禽精子活力调控基因的研究进展

doi:10.16431/j.cnki.1671-7236.2023.12.018

Abstract

Abstract: The quality of semen determines the fertilization rate and reproductive efficiency of domestic animals,and is an important factor affecting the efficiency of domestic animals production.Sperm motility refers to the percentage of sperm moving forward in a straight line in semen,which is one of the most important evaluation indicators of domestic animals semen quality.Improving sperm motility is the key to improve semen quality.Sperm motility is a complex trait regulated by multiple genes and pathways,which is a medium to high heritability trait.Therefore,genetic improvement has become an effective way to improve sperm motility.Compared with the traditional means of genetic improvement,new breeding technologies such as genome editing and molecular marker assisted selection have the characteristics of high efficiency,strong purpose and short cycle,providing new opportunities for domestic animals breeding.At present,the number of known genes affecting sperm motility of domestic animals is limited,which limits the application of new breeding technology in genetic improvement of sperm motility.Therefore,the identification of key genes regulating the sperm motility is important for domestic animals breeding.Genes mainly regulate sperm motility from two aspects of sperm structure and sperm function,including sperm structure defects,energy metabolism,ion channels,DNA integrity,semen composition and other aspects.This paper introduces the functional genes that regulate sperm motility in both sperm structure and sperm function,and summarizes their mechanism and research progress,aiming to provide reference for molecular breeding related to sperm motility.

Key words: sperm motility; gene; sperm structure abnormality; sperm function defect

CLC Number:

S813.3

LIU Yizheng, CAO Junyi, GAI Kai, CONG Bailin, GUO Shihao, XING Kai, QI Xiaolong, WANG Xiangguo, XIAO Longfei, LONG Cheng, GUO Yong, SHENG Xihui. Research Progress on the Genes Regulating Sperm Motility in Domestic Animals[J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(12): 4958-4972.

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Research Progress on the Genes Regulating Sperm Motility in Domestic Animals

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