三维重建和3D打印技术在比格犬肝脏模型构建中的应用

doi:10.16431/j.cnki.1671-7236.2023.05.039

Abstract

Abstract: 【Objective】 Three-dimensional reconstruction and 3D printing techniques were used to construct a three-dimensional model of the liver in Beagle dogs to provide three-dimensional data and morphological basis for the diagnosis,treatment and related surgery of liver diseases in dogs,and at the same time,it laid a foundation for the dose reduction and use of experimental animals and improving animal welfare.【Method】 A female 8-month-old healthy Beagle dog weighing 14.5 kg was intravenously injected with iohexol after general anesthesia,and two-dimensional image data were collected from the liver of the dog by 128-slice spiral computed tomography (CT),followed by digital segmentation and three-dimensional reconstruction using IPS software,and images were measured using the Touch Viewer software.Finally,the reconstructed data were transmitted to a 3D printer to generate 3D printed models of portal vein,hepatic vein,hepatic artery and other tissues one by one,and finally the 3D physical model of the dog liver was obtained after coloring,layer optimization and assembly processing.【Result】 The three-dimensional reconstruction model of the liver constructed by CT enhanced angiography data had realistic shape and strong stereoscopic sense,could be arbitrarily scaled and rotated at an angle in the three-dimensional space,and could be mapped plane by adjusting the threshold to form a section of each site or separately display the direction and distribution of the hepatic artery,hepatic vein,portal vein,and bile duct,which was convenient to observe the spatial location of each vascular structure and display the complex local anatomical structure of the liver.Touch Viewer measurements showed the volume of the liver was 556.14 mL with a surface area of 600.85 cm² and the volume of the gallbladder was 12.67 mL with a surface area of 32.47 cm².The 3D printed model showed that the vascularity of each tissue was clear and bright in color,which was basically consistent with the digital three-dimensional model,and a more real and ideal liver model was obtained.【Conclusion】 Three-dimensional reconstruction and 3D printing technology could successfully construct a canine liver model,which could visually display the complex three-dimensional shape and spatial structure of the liver and could be used as a good simulation platform and practical tool for digital and precise pet medicine as well as veterinary anatomy and imaging teaching.

Key words: dog; liver; CT scan; 3D reconstruction; 3D printing

CLC Number:

S829.2

XU Jiahui, XIE Jiaxin, JIANG Chengkun, ZHANG Sen, YAO Hua, ZHANG Hua. Application of Three-dimensional Reconstruction and 3D Printing Technology in Beagle Dog Liver Model Construction[J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 2130-2138.

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Application of Three-dimensional Reconstruction and 3D Printing Technology in Beagle Dog Liver Model Construction

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