猪伪狂犬病病毒SL株TK基因的克隆与生物信息学分析

Abstract

Abstract: TK gene of pseudorabies virus SL strain was cloned. Based on the sequence, the homology, phylogeny tree, codon bias, amino acid structure, hydrophilic and hydrophobicity, transmembrane region and signal peptide were analyzed. The results showed that TK gene was successfully cloned and it consisted 963 nucleotides encoding a protein of 320 amino acids. The TK gene shared over 99.3% homology with that of the other PRV strains. PRV TK was predicted to not have the transmembrane region and signal peptide, and not be inside of virus envelope.

Key words: pseudorabies virus; TK gene; bioinformatics analysis

CLC Number:

ZHANG Shi-qiang, YI Yue, XU Zhi-wen, ZHU Ling. Bioinformatics Analysis of TK Gene of Pseudorabies Virus SL Strain from Pigs[J]. , 2012, 39(6): 26-30.

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Bioinformatics Analysis of TK Gene of Pseudorabies Virus SL Strain from Pigs

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