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Current Research Status of Brucella Vaccine

FU Ying-ying1, 2, QIN Gui-xin1, QIAN Jun2,3, ZHAO Si-yan2,3, ZHENG Guan-yu1,2,SUN Yu-cheng2,3,WAN Jia-yu2,3, LIU Wen-sen2,3, LIU Lin-na2,3   

  1. (1.College of Animal Science and Technology, Jilin Agricultural University, Changchun 130118, China;2.Institute of Military Veterinary,Academy of Military Medical Science, Changchun 130122, China;3.Key Laboratory of Jilin Province for Zoonosis Prevention and Control, Changchun 130122, China)
  • Received:2013-08-22 Online:2014-03-20 Published:2014-05-15

Abstract: Brucellosis caused by Brucella is a zoonotic infectious disease, and not only the serious influence to the healthy development of animal husbandry, but also to human health and public health security that exist a lot of threats.To the current prevention and control measures for animal vaccination, domestic and foreign existing multiple weak vaccines, each vaccine has its advantages and disadvantages, there is no vaccine for human currently, the laboratorys have used genetic engineering and other technical means to actively develop new vaccines, such as recombinant attenuated vaccines and marker vaccines, DNA vaccines and so on, this paper introduces the research status of new vaccines.

Key words: brucellosis; Brucella; new vaccines