›› 2014, Vol. 41 ›› Issue (11): 44-49.

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The Genotype Analysis of Coat Color Gene MC1R in Swine

YIN Chong1,2, GAO Feng1, LI Ao-nan1, ZHANG Cheng-cai1, ZHOU Meng-jiao1, BAI Chun-yan1, SUN Bo-xing1, ZHAO Zhi-hui1, XING Shen-yang1   

  1. 1. College of Animal Science, Jilin University, Changchun 130062, China;
    2. School of Life Science, Northwestern Polytechnical University, Xi'an 710072, China
  • Revised:2014-05-16 Online:2014-11-20 Published:2014-12-06

Abstract: For analysis melanocortin receptor 1(MC1R) genotype in swine spices with different coat color and study the gene functions on swine coat color. This research analysed the genotype of MC1R in Junmu 1 White pigs, Durocs pigs, Tibet mini-pigs and Large White pigs with PCR-SSCP and PCR-RFLP technique. The result showed that Junmu 1 White pigs and Large White pigs presented mutation on nt894insCC and G1197A site, Durocs pigs presented mutation on G668C, C1318T, and G1554A site, Tibet mini-pigs presented mutation on C1318T and G1554A site, with a different genotype on nt894insCC site. The MC1R genotype result provided a basis for studying MC1R regulation mechanism to swine coat color.

Key words: MC1R gene; coat color; swine

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