›› 2014, Vol. 41 ›› Issue (11): 232-236.

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Research Progress of Long Noncoding RNA in Muscle Development

LI Yan-yan1,2, GU Zhi-liang1   

  1. 1. College of Biological Science and Food Engineering, Changshu Institute of Technology, Changshu 215500, China;
    2. College of Preclinical Medicine and Biological Science, Soochow University, Suzhou 215000, China
  • Received:2014-03-27 Online:2014-11-20 Published:2014-12-06

Abstract: Long noncoding RNA (lncRNA) is a class of RNA being more than 200 nucleotides in length, which also has no protein coding function. The researches suggest that lncRNA can mediate genomic imprinting, transcriptional activation and interference, post transcriptional regulation, chromosome dosage compensation effect, developmental regulation and many other biological processes. The detection and classification, biological function of lncRNAs, and the research progress of lncRNAs associated with muscle development would be reviewed in this paper.

Key words: long noncoding RNA; biological functions; muscle development

CLC Number: