Abstract: The aim of the study was to investigate the effects of different diets on expression levels of lipid synthesis metabolism related genes in Wujin pigs. Thirty-six Wujin pigs with the body weights of 23 kg (female and male half and half) were randomly assigned into two groups with three replicates per group and six heads in each replicate. The treatment 1 group was fed with the Wujin diet, and the treatment 2 group was fed with the NRC diet. At the body weight of 30, 60 and 100 kg, pigs were slaughtered and adipose tissue samples were taken for analyzing the expression levels of three lipid metabolism genes using Real-time PCR technology. The results showed that at the body weight of 30 kg, the expression levels of FAS gene in treatment 1 group were dramatically lower than that in the treatment 2 group (P<0.05). At the body weights of 60 and 100 kg, the expression levels of FAS gene in treatment 1 group were higher than that in the treatment 2 group, but it was significantly different at the body weight of 60 kg (P<0.05). At the body weights of 30, 60 and 100 kg, the expression levels of SREBP-1c gene in treatment 1 group were higher than the treatment 2 group, but the difference was significant at the body weights of 30 and 60 kg (P<0.05). At the body weights of 30, 60 and 100 kg, the expression levels of DGAT-1 gene in treatment 1 group were lower than the treatment 2 group, but the difference was significant at the body weight of 100 kg (P<0.05).The results indicated that the diets could differently regulate the expression of lipid synthesis metabolism related genes in porcines with various body weights.

Key words: Wujin pigs; adipose tissue; lipid synthesis metabolism; gene expression