›› 2011, Vol. 38 ›› Issue (3): 65-68.

• 生物技术 • Previous Articles     Next Articles

New Advances in RNA Interference Studies in Parasitic Nematodes

HE Xian-hui1, ZHU Xing-quan2, XU Min-jun1,2   

  1. 〗(1.College of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China;2.State Key Laboratory of Veterinary Etiological Biology, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou 730046, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-03-20 Published:2011-03-20
  • Contact: XU Min-jun

Abstract: RNA interference(RNAi) is a powerful tool for genomics research. It was found that gene expression can be interfered by double-stranded RNA(dsRNA) which led to silence of the target gene. RNA interference in parasitic nematodes with exogenous dsRNA helps understand the characteristics of different developmental stages and the biological functions of aimed genes. On the other hand, the study of RNA interference in parasitic nematodes will promote the RNAi technology itself. The present article reviewed the research progresses in RNAi studies in parasitic nematodes in recent years, which would provide references for related research.

Key words: parasite; nematodes; RNA interference(RNAi); double-stranded RNA(dsRNA); gene silence

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