›› 2011, Vol. 38 ›› Issue (1): 39-41.

• 生理生化 • Previous Articles     Next Articles

Effect of Raw Soybean on Oxygen Free Radical Level of Digestive Tract and Pancreas in Mice

GU Chun-mei1,2, SHI Yong-hui2, LE Guo-wei2
  

  1. （1. School of Food Science and Engineering，Jilin Agricultural University，Changchun 130118, China;2. State Key Laboratory of Food Science and Technology, Research Institute of Food Nutrition and Safety, School of Food Science and Technology, Jiangnan University, Wuxi 214122, China）
  • Received:1900-01-01 Revised:1900-01-01 Online:2011-01-01 Published:2011-01-01
  • Contact: LE Guo-wei

Abstract: To study the effects of raw soybean on oxygen free radical level of digestive tract and pancreas in mice, thirty male C57BL/6J mice were randomly divided into control, raw soybean（RS） and cysteamine groups（CS）. Each group was fed for 2 weeks, then duodenum, liver, pancreas samples were collected to examine the oxidative and antioxidative capability. The results showed that compared with control mice, MDA content and iNOS activity in duodenum, liver and pancreas of mice fed raw soybean were significantly increased, but levels of SOD, GSH and so on were significantly decreased. Imbalance state of oxidant and antioxidant was improved by cysteamine. These data demonstrated that raw soybean diet could significantly increase oxygen free radical level of digestive tract and pancreas in mice, and induce oxidative stress.

Key words: raw soybean; antinutritional factors; oxygen free radical; digestive tract; pancreas; mice

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