骨形态发生蛋白4与哺乳动物卵泡发育的研究进展

›› 2010, Vol. 37 ›› Issue (3): 141-144.

• 遗传繁育 • Previous Articles Next Articles

Progress on Bone Morphogenetic Protein 4 on Mammalian Follicular Development

ZHANG Chi, ZHOU Jian-she, QIN Nan, LI Ming, CHEN Qi-xin

(College of Animal Science and Veterinary Medicine, Henan Agricultural University, Zhenzhou 450002,China)

Received:1900-01-01 Revised:1900-01-01 Online:2010-03-20 Published:2010-03-20
Contact: CHEN Qi-xin

Abstract

Abstract: Bone morphogenetic proteins 4(BMP-4) is belonging to the transfer growth factor(TGF-β) superfamily.It involves in the cell of body growth,polarization,apoptosis,migration and the formation of extracellular matrix and many other pathological and physiological activity. Recent studies have shown that BMP-4 gene is closely related to the reproductive performance of mammals.It is a crucial factor in follicular growth and development in the mammalian ovary.In this review，the structure，function and regulation of BMP-4 were introduced．The relationships between BMP-4 gene and follicular development were also discussed in mammals.

Key words: bone morphogenetic protein 4; signal transduction; follicular development

CLC Number:

S814

ZHANG Chi;ZHOU Jian-she;QIN Nan;LI Ming;CHEN Qi-xin. Progress on Bone Morphogenetic Protein 4 on Mammalian Follicular Development[J]. , 2010, 37(3): 141-144.

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Progress on Bone Morphogenetic Protein 4 on Mammalian Follicular Development

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