IFN-γ研究进展及其在猪繁殖与呼吸综合征研究中的应用

›› 2010, Vol. 37 ›› Issue (12): 145-150.

• 疾病防治 • Previous Articles Next Articles

Advance in Interferon-gamma of Porcine Reproductive and Respiratory Syndrome

BAI Xue1, ZHAO Jian-zeng1,2, LIANG Zhi-xuan3, QU Xue-qi1, LI Yong1, MEI Lin1, WEN Tao1,2, HE Bin1, YANG Ju1, LUO Sheng-jun4, XING Hai-yun1, GAO Ying-jie1

(1.College of Animal Science and Veterinary Medicine, Jilin University, Changchun 130062, China;2.Beijing Bigvet Biotech Co.Ltd., Beijing 100176, China; 3.Tianjin Animal Diseases Control Center, Tianjin 300402,China; 4.Institute of Veterinary Medicine, Guangdong Academy of Agricultural Sciences, Guangzhou 510640, China)

Received:1900-01-01 Revised:1900-01-01 Online:2010-12-20 Published:2010-12-20
Contact: GAO Ying-jie

Abstract

Abstract: Interferon-γ (interferon gamma, IFN-γ) known as type Ⅱ interferon or immune interferon is a kind of interferons which secreted mainly by activated T cells and NK cells. As one of the most important cytokines in animal body, IFN-γ is the major macrophage-activating factor (MAF) which has the abilities of immunolo-regulation, antivirus, anti-tumor and so on. At present, more and more attention has been payed on the research of gene engineering and gene therapy using interferon, and interferon has already been used for the researches both on clinical therapy of human disease and prevention and control of animal disease. In this paper, we reviewed the characteristic, biological activity and detection method of IFN-γ, and subsequently the application of IFN-γ in the research of PRRS was also mentioned.

Key words: interferon gamma; biological activity; porcine reproductive and respiratory syndrome

CLC Number:

S859.79⁺7

BAI Xue;ZHAO Jian-zeng;;LIANG Zhi-xuan;QU Xue-qi;LI Yong;MEI Lin; WEN Tao;;HE Bin;YANG Ju;LUO Sheng-jun;XING Hai-yun;GAO Ying-jie. Advance in Interferon-gamma of Porcine Reproductive and Respiratory Syndrome[J]. , 2010, 37(12): 145-150.

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Advance in Interferon-gamma of Porcine Reproductive and Respiratory Syndrome

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