›› 2009, Vol. 36 ›› Issue (5): 194-198.

• 经验交流 • Previous Articles     Next Articles

Effect of the Long-term Taking ZhenTian Capsule on PathologicalExaminination in Rats

WANG Ting1,2, ZHAO De-ming1, SONG Huai-yan2   

  1. (1.National Animal Transmissible Spongiform Encephalopathies Laboratory, China Agricultural University, Beijing 100193, China;2.Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences, Beijing 100021, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-05-20 Published:2009-05-20
  • Contact: ZHAO De-ming

Abstract: To study the pathological examination effect of ZhenTian capsule, the rats were orally given ZhenTian capsule for 180 days with the doses of 1.315, 2.63 and 5.26 g (crude medicinal materials)/kg (13, 26.1 and 52.2 times of clinic does) while the control group was given the distilled water of the same volume and for 4 weeks of stopping administration. Meanwhile, rats’ behavior and appearance were observed, and night shit and urine everyday amounts were measured, coefficient of the main organs and pathological examination of the rats were investigated. All the examinations and index are within the normal level. No significantly histological change related to visceral is observed.

Key words: ZhenTian capsule; long-term toxicity; rat; pathological

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