›› 2009, Vol. 36 ›› Issue (11): 27-29.

• 生理生化 • Previous Articles     Next Articles

The Effects of IL-10 on Dendritic Cells Infected by Foot-and-mouth Virus

LANG Xu-long, WANG Xing-long, SUN Chun-hui, ZHANG Fu-xian, BU Zhao-yang,
LU Hao, TANG Jie, DANG Yuan, WANG Ying-chao
  

  1. (The Military Veterinary Institute, Academy of Military Medical Sciences of PLA, Changchun 130062, China)
  • Received:1900-01-01 Revised:1900-01-01 Online:2009-11-20 Published:2009-11-20
  • Contact: WANG Xing-long

Abstract: Dendritic cells (DC) are the most potent antigen presenting cells (APC) of the immune system, so it has a special place in induce of immune response. We thought that IL-10 have important effects through the process of viral infection. In this research the IL-10 and IL-10 neutralizing antibody were used to regulate the immune state of DCs when they were infected by FMDVs, the results showed that IL-10 can affect the immune regulation in the course of FMDV infection.

Key words: IL-10; foot-and-mouth virus; dendritic cells

CLC Number: