China Animal Husbandry and Veterinary Medicine ›› 2024, Vol. 51 ›› Issue (1): 220-228.doi: 10.16431/j.cnki.1671-7236.2024.01.023
• Genetics and Breeding • Previous Articles Next Articles
LI Wen1, HE Xiaoming1, LU Ying1, ZHAO Dongxiang1, ZHANG Jinbiao1, WANG Kai1, GAO Zhendong1, YUE Dan2, LIU Xingneng3, DENG Weidong1
Received:
2023-07-25
Online:
2024-01-05
Published:
2023-12-27
CLC Number:
LI Wen, HE Xiaoming, LU Ying, ZHAO Dongxiang, ZHANG Jinbiao, WANG Kai, GAO Zhendong, YUE Dan, LIU Xingneng, DENG Weidong. Research Progress on the Effect of Robo2 Gene on Melanin Formation[J]. China Animal Husbandry and Veterinary Medicine, 2024, 51(1): 220-228.
[1] SWOPE V B, ABDEL-MALEK Z A.MC1R:Front and center in the bright side of dark eumelanin and DNA repair[J].International Journal of Molecular Sciences, 2018, 19(9):2667. [2] LAPIERRE-LANDRY M, CARROLL J, SKALA M C.Imaging retinal melanin:A review of current technologies[J].Journal of Biological Engineering, 2018, 12:29. [3] 田颖刚, 徐德利, 廖春艳.泰和乌骨鸡黑色素细胞形态与分布特征[J].中国家禽, 2015, 37(1):5-8. TIAN Y G, XU D L, LIAO C Y.Distribution and characteristic of melanocytes in Taihe Black-bone silky fowl(Gallus gallus Domesticus Brisson)[J].China Poultry, 2015, 37(1):5-8.(in Chinese) [4] 毛华明, 邓卫东, 孙守荣, 等.云南乌骨绵羊的发现及其特征性状的研究[J].云南农业大学学报, 2005, 1:89-93. MAO H M, DENG W D, SUN S R, et al.Studies on the specific characteristics of Yunnan Black-bone sheep[J].Journal of Yunnan Agricultural University, 2005, 1:89-93.(in Chinese) [5] 熊和丽.兰坪乌骨绵羊群体遗传结构及其种质特色性状遗传基础分析[D].昆明:云南农业大学, 2020. XIONG H L.Population structure and genetic profile of unique breed traits in Lanping Black-boned sheep(Ovis aries)[D]. Kunming:Yunnan Agricultural University, 2020.(in Chinese) [6] 王晓鹤, 周玉云, 黄晓慧, 等.Slit-Robo信号通路在神经轴突生长和血管新生中作用研究进展[J].生物医学工程与临床, 2017, 21(4):454-457. WANG X H, ZHOU Y Y, HUANG X H, et al.Research progress on the role of the Slit-Robo signaling pathway in neural axon guidance and angiogenesis[J].Biomedical Engineering and Clinical Medicine, 2017, 21(4):454-457.(in Chinese) [7] KONG R, YI F, WEN P, et al.Myo9b is a key player in SLIT/ROBO-mediated lung tumor suppression[J].The Journal of Clinical Investigation, 2015, 125(12):4407-4420. [8] 柴源, 蒋莱, 周玉云, 等.Slit-Robo信号通路在血管生成中作用的研究进展[J].中国脑血管病杂志, 2015, 12(9):485-489. CHAI Y, JIANG L, ZHOU Y Y, et al.Research progress on the role of Slit-Robo signaling pathway in angiogenesis[J].Chinese Journal of Cerebrovascular Diseases, 2015, 12(9):485-489.(in Chinese) [9] CORDERO R J B, CASADEVALL A.Melanin[J].Current Biology, 2020, 30(4):R142-R143. [10] BONAVENTURE J, DOMINGUE M J, LARUE L.Cellular and molecular mechanisms controlling the migration of melanocytes and melanoma cells[J].Pigment Cell & Melanoma Research, 2013, 26(3):316-325. [11] 杨舒黎, 毛华明, 舒文, 等.云南乌骨绵羊乌质性状与TYR基因多态性的相关分析[J].遗传, 2006, 3:291-298. YANG S L, MAO H M, SHU W, et al.Melanin traits of Yunnan Black bone sheep and TYR gene polymorphism[J].Hereditas, 2006, 3:291-298.(in Chinese) [12] 岳丹, 刘兴能, 熊和丽, 等.兰坪乌骨绵羊黑色素及其候选基因研究进展[J].家畜生态学报, 2021, 42(5):1-6. YUE D, LIU X N, XIONG H L, et al.Research progress on melanin and its candidate gene of Lanping Black-bone sheep(Ovis aris)[J].Acta Ecologae Animalis Domastici, 2021, 42(5):1-6.(in Chinese) [13] 章誉兴, 吴宏, 于黎.哺乳动物毛色调控机制及其适应性进化研究进展[J].遗传, 2021, 43(2):118-133. ZHANG Y X, WU H, YU L.Progress on coat color regulation mechanism and its association with the adaptive evolution in mammals[J].Hereditas, 2021, 43(2):118-133.(in Chinese) [14] 蒋卓远, 查艳, 石小峰, 等.神经嵴细胞和神经嵴病及其致病机制的研究进展[J].遗传, 2022, 44(2):117-133. JIANG Z Y, ZHA Y, SHI X F, et al.Research progress on neural crest cells and neurocristopathies and its pathogenesis[J].Hereditas, 2022, 44(2):117-133.(in Chinese) [15] DYSON L, HOLMES A, LI A, et al.A chemotactic model of trunk neural crest cell migration[J].The Journal of Genetics and Development, 2018, 56(9):e23239. [16] YUAN Y, LOH Y H E, HAN X, et al.Spatiotemporal cellular movement and fate decisions during first pharyngeal arch morphogenesis[J].Science Advances, 2020, 6(51):eabb0119. [17] COSTIN G E, HEARING V J.Human skin pigmentation:Melanocytes modulate skin color in response to stress[J].The FASEB Journal, 2007, 21(4):976-994. [18] 王春丽, 柳伟.酪氨酸酶的研究进展[J].生物加工过程, 2014, 12(4):94-100. WANG C L, LIU W.Research progress of tyrosinase[J].Chinese Journal of Bioprocess Engineering.2014, 12(4):94-100.(in Chinese) [19] RZEPKA Z, BUSZMAN E, BEBEROK A, et al.From tyrosine to melanin:Signaling pathways and factors regulating melanogenesis[J]. Advances in Hygiene and Experimental Medicine, 2016, 70:695-708. [20] 董懿, 康馨月, 王春生.哺乳动物黑色素生物合成及其调控机制研究进展[J].生命科学, 2022, 34(8):990-1000. DONG Y, KANG X Y, WANG C S.Progress on the research of biosynthesis and regulation of mammalian[J].Chinese Bulletin of Life Sciences, 2022, 34(8):990-1000.(in Chinese) [21] AMINO Y, TAKINO Y, KANEKO M, et al.Synthesis, characterization, and evaluation of thiazolidine derivatives of cysteine for suppressing eumelanin production[J].Chemical and Pharmaceutical Bulletin, 2016, 64:1681-1691. [22] EMARESI G, DUCREST A L, BIZE P, et al.Pleiotropy in the melanocortin system:Expression levels of this system are associated with melanogenesis and pigmentation in the tawny owl(Strix aluco)[J].Molecular Ecology, 2013, 22:4915-4930. [23] LE P E, WAKAMATSU K, ITO S, et al.Regulation of eumelanin/pheomelanin synthesis and visible pigmentation in melanocytes by Ligands of the melanocortin 1 receptor[J].Pigment Cell & Melanoma Research, 2008, 21:477-486. [24] YOSHIDA H, KUNISADA T, KUSAKABE M, et al.Distinct stages of melanocyte differentiation revealed by analysis of nonuniform pigmentation patterns[J].The Company of Biologists, 1996, 122(4):1207-1214. [25] BELLE B, PITISCI A, CATRICALA C, et al.Wnt/β-catenin signaling is stimulated by α-melanocyte-stimulating hormone in melanoma and melanocyte cells:Implication in cell differentiation[J].Pigment Cell & Melanoma Research, 2011, 24(2):309-325. [26] DE R, PLOPER D.Sperm motility requires Wnt/GSK3 stabilization of proteins[J].Developmental Cell, 2015, 35:401-402. [27] PLOPER D, DE R E V M.The MITF family of transcription factors:Role in endolysosomal biogenesis, Wnt signaling, and oncogenesis[J].Pharmacological Research, 2015, 99:36-43. [28] ZHANG P, LIU W, YUAN X, et al.Endothelin-1 enhances the melanogenesis via MITF-GPNMB pathway[J].BMB Reports, 2013, 46:364-369. [29] WAN P, HU Y, HE L.Regulation of melanocyte pivotal transcription factor MITF by some other transcription factors[J].Molecular and Cellular Biochemistry, 2011, 354:241-246. [30] SEEGER M, TEAR G, FERRES-MARCO D, et al.Mutations affecting growth cone guidance in drosophila:Genes necessary for guidance toward or away from the midline[J].Neuron, 1993, 10(3):409-426. [31] RAJAGOPALAN S, VIVANCOS V, NICOLAS E, et al.Selecting a longitudinal pathway:Robo receptors specify the lateral position of axons in the drosophila CNS[J]. Cell, 2000, 103(7):1033-1045. [32] 梁玉花.Robo2对果蝇痛觉神经元轴突发育及逃避反应的影响[D].辽宁:大连大学, 2020. LIANG Y H.Effects of Robo2 on axonal development of nociceptor and escape responses in drosophila[D]. Liaoning:Dalian University, 2020.(in Chinese) [33] LEE J S, RAY R, CHIEN C B.Cloning and expression of three zebrafish roundabout homologs suggest roles in axon guidance and cell migration[J].Developmental Dynamics, 2001, 221(2):216-230. [34] 李晓童, 周启升, 于奇.等.神经轴突导向分子Robo的功能及其分子作用机制研究进展[J].生理学报, 2014, 66(3):373-385. LI X T, ZHOU Q S, YU Q, et al.Current progress in functions of axon guidance molecule Robo and underlying molecular mechanism[J]. Acta Physiologica Sinica, 2014, 66(3):373-385.(in Chinese) [35] WU M F, LIAO C Y, WANG L Y, et al.The role of Slit-Robo signaling in the regulation of tissue barriers[J].Tissue Barriers, 2017, 5(2):e1331155. [36] 于奇, 周启升, 赵晓, 等.神经轴突导向分子Slit的功能及其分子作用机制研究进展[J].生理学报, 2012, 64(2):220-230. YU Q, ZHOU Q S, ZHAO X, et al.Current progress in functions of axon guidance molecule Slit and underlying molecular mechanism[J].Acta Physiologica Sinica, 2012, 64(2):220-230.(in Chinese) [37] ANDREWS W, BARBER M, HERNADEZ-MIRANDA L R, et al.The role of Slit-Robo signaling in the generation, migration and morphological differentiation of cortical interneurons[J].Developmental Biology, 2008, 313(2):648-658. [38] 韩哲, 杨雪松, 耿建国, 等.Slit/Robo信号在血管新生中的功能研究[J].生命科学, 2010, 22(10):1020-1024. HAN Z, YANG X S, GENG J G, et al.The functional research of Slit/Robo on angiogenesis[J].Chinese Bulletin of Life Sciences, 2010, 22(10):1020-1024.(in Chinese) [39] TONG M, JUN T, NIE Y, et al.The role of the Slit/Robo signaling pathway[J].Journal of Cancer, 2019, 10(12):2694-2705. [40] MORLOT C, THIELENS N M, RAVELLI R B G, et al.Structural insights into the Slit-Robo complex[J].Proceedings of the National Academy of Sciences, 2007, 104(38):14923-14928. [41] FUKUHARA N, HOWITT J A, HUSSAIN S A, et al.Structural and functional analysis of Slit and heparin binding to immunoglobulin-like domains 1 and 2 of drosophila Robo[J]. Journal of Biological Chemistry, 2008, 283(23):16226-16234. [42] ZELINA P, BLOCKUS H, ZAGAR Y, et al.Signaling switch of the axon guidance receptor Robo3 during vertebrate evolution[J].Neuron, 2014, 84(6):1258-1272. [43] 张超, 王腾飞, 张姗姗, 等.中枢神经系统Slit/Robo GTPase激活蛋白信号通路研究进展[J].国际脑血管病杂志, 2006, 9:707-710. ZHAN C, WANG T F, ZHANG S S, et al.Recent advances in Slit/Robo GTPase activating proteins signal pathway in the central nervous system[J].International Journal of Cerebrovascular Diseases, 2006, 9:707-710.(in Chinese) [44] 于晓霞, 曹济民.生长锥导向分子Slit/Robo对神经生长的调控作用[J].国外医学(生理、病理科学与临床分册), 2004, 3:208-211. YU X X, CAO J M.Regulatory effects of growth cone guiding molecule Slit/Robo on nerve growth[J].Journal of Clinical and Pathological Research, 2004, 3:208-211.(in Chinese) [45] GONDA Y, NAMBA T, HANASHIMA C.Beyond axon guidance:Roles of Slit-Robo signaling in neocortical formation[J].Frontiers in Cell and Developmental Biology, 2020, 8:607415. [46] DALKIC E, KUSCU C, SUCULARLI C, et al.Alternatively spliced Robo2 isoforms in zebrafish and rat[J].Development Genes and Evolution, 2006, 216:555-563. [47] POCHA S M, MONTELL D J.Cellular and molecular mechanisms of single and collective cell migrations in drosophila:Themes and variations[J].Annual Review of Genetics, 2014, 48:295-318. [48] MA N X, YIN J C, CHEN G.Transcriptome analysis of small molecule-mediated astrocyte-to-neuron reprogramming[J].Frontiers in Cell and Developmental Biology, 2019, 7:82. [49] PIGNATA A, DUCUING H, BOUBAKA L, et al.A spatiotemporal sequence of sensitization to Slits and semaphorins orchestrates commissural axon navigation[J].Cell Reports, 2019, 29:347-362. [50] 王婷, 杨光路.神经毡蛋白2在神经系统中的相关性研究[J].临床医学进展, 2020, 10(5):741-748. WANG T, YANG G L.Correlation of neuropilin 2 in the nervous system[J].Advances in Clinical Medicine, 2020, 10(5):741-748.(in Chinese) [51] SOLDATOV R, KAUCKA M, KASTRITI M E, et al.Spatiotemporal structure of cell fate decisions in murine neural crest[J].Science, 2019, 364(6444):eaas9536. [52] GRILL C, BERGSTEINSDOTTIR K, OGMUNDSDOTTIR M H, et al.MITF mutations associated with pigment deficiency syndromes and melanoma have different effects on protein function[J].Human Molecular Genetics, 2013, 21(22):4357-4367. [53] 许甜甜, 张彤彤, 王蒙, 等.转录因子Foxq1通过Wnt/β-catenin信号通路影响绒山羊毛囊干细胞增殖的研究[J].畜牧兽医学报, 2023, 54(6):2653-2661. XU T T, ZHANG T T, WANG M, et al.Transcription factor Foxq1 affects the proliferation of hair follicle stem cells in cashmere goats via Wnt/β-catenin signaling pathway[J].Acta Veterinaria et Zootechnica Sinica, 2023, 54(6):2653-2661.(in Chinese) [54] 赵美娟, 户晶晶, 倪辉, 等.黑色素生成信号通路研究进展[J].生物工程学报, 2019, 35(9):1633-1642. ZHAO M J, HU J J, NI H, et al.Research progress in melanogenesis signaling pathway[J]. Chinese Journal of Biotechnology, 2019, 35(9):1633-1642.(in Chinese) [55] HUANG Y C, YANG C H, CHIOU Y L.Citrus flavanone naringenin enhances melanogenesis through the activation of Wnt/β-catenin signaling in mouse melanoma cells[J].Phytomedicine, 2011, 18(14):1244-1249. [56] GUO H, YANG K, DENG F, et al.Wnt3a inhibits proliferation but promotes melanogenesis of melan-a cells[J].International Journal Molecular Medicine, 2012, 30(3):636-642. [57] ZHANG Q Q, ZHOU D, LEI Y, et al.Slit2/Robo1 signaling promotes intestinal tumorigenesis through Src-mediated activation of the Wnt/β-catenin pathway[J].Oncotarget.2015, 6(5):3123-3135. [58] JIA L, CHENG L, RAPER J.Slit/Robo signaling is necessary to confine early neural crest cells to the ventral migratory pathway in the trunk[J]. Developmental Biology, 2005, 282(2):411-421. [59] HARRIS M L, ERICKSON C A.Lineage specification in neural crest cell pathfinding[J].Developmental & Stem Cell Biology Graduate Program, 2007, 236(1):1-19. [60] SHI H, L V C, KANG W, et al.Robo2 expression and its correlation with MITF in human cutaneous melanoma[J]. Journal of Dermatological Science, 2018, 89(2):152-154. [61] HARTMAN M L, CZYZ M.MITF in melanoma:Mechanisms behind its expression and activity[J].Cellular and Molecular Life Sciences, 2015, 72(7):1249-1260. [62] BEAMISH I V, HINCK L, KENNEDY T E.Making connections:Guidance cues and receptors at nonneural cell-cell junctions[J].Cold Spring Harbor Perspectives in Biology, 2018, 10(11):a029165. [63] RHEINHEIMER B A.Alternative transcription of the SLIT2/miR-218-1 transcriptional axis mediates pancreatic cancer invasion[D].Tucson:The University of Arizona, 2016. [64] 龚石, 刘巧.胚胎干细胞诱导生成色素细胞的研究进展[J].中国美容医学, 2009, 18(7):1032-1034. GONG S, LIU Q.Induction of cutaneous melanocytes from ES cells[J].Chinese Journal of Aesthetic Medicine, 2009, 18(7):1032-1034.(in Chinese) [65] 梅雨, 周希瑗.Slit2基因转染对人视网膜色素上皮细胞VEGF表达的影响及其作用机制[J].重庆医科大学学报, 2015, 38(11):1594-1599. MEI Y, ZHOU X Y.Effect of Slit2 gene transfection on vascular endothelial growth factor in retinal pigment epithelium cells and its mechanism[J].Journal of Chongqing Medical University, 2015, 38(11):1594-1599.(in Chinese) [66] YANG G, ZHANG G, PITTELKOW M R, et al.Expression profiling of UVB response in melanocytes identifies a set of p53-target genes[J].Journal of Investigative Dermatology, 2006, 126(11):2490-2506. [67] MOORE D L, BLACKMORE M G, HU Y, et al.KLF family members regulate intrinsic axon regeneration ability[J].Science, 2009, 326(5950):298-301. [68] GROSSMANN A H, ZHAO H, JENKINS N, et al.The small GTPase ARF6 regulates protein trafficking to control cellular function during development and in disease[J].Small GTPases, 2019, 10(1):1-12. [69] MAHMUTOYIC L, BILAJAC E, HROMIC-TAHJEFENDIC A.Meet the insidious players:Eeview of viral infections in head and neck cancer etiology with an update on clinical trials[J].Microorganisms, 2021, 9(5):1001. [70] DENK A E, BRAIG S, SCHUBERT T, et al.Slit3 inhibits activator protein 1-mediated migration of malignant melanoma cells[J].International Journal of Molecular Medicine, 2011, 28(5):721-726. |
[1] | LI Hanmei, YAN Hua, LIU Xin, WANG Lixian. Research Progress on Maternal Behavior in Sows and Its Influencing Factors [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(8): 3171-3179. |
[2] | YAO Wenna, YAN Shuo, XUE Yue, ZHAO Yulong, SU He, SONG Yongli, LI Xihe, BAO Huala, BAO Siqin. Research Progress on Fecal Microbiota Transplantation in Mammals [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(8): 3384-3390. |
[3] | LI Yuanyuan, MAO Yan, LIANG Zengenni, YANG Chenglin, WU Jing, YUAN Zhihang, YUAN Liyun. Research Progress on the Pharmacological Effects of Viola yedoensis Makino [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(7): 2998-3006. |
[4] | WANG Saiqiao, ZHAO Lu, ZHAI Zhenhan, ZHANG Binglei, JIA Wanhang, WANG Yuqin. Tissue Expression and Bioinformatics Analysis of miR-449a/b Precursor Sequences in Sheep [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(6): 2175-2184. |
[5] | LU Hui, CAI Gaofeng, WU Caihong, QIU Shulei, YUAN Chen, CHEN Xiaolan, LIU Yun, QIN Kaili. Effect of Agrocybe aegerita Polysaccharid on Immunomodulatory of Splenic Lymphocytes in Mice [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(5): 1828-1835. |
[6] | CHEN Shaojun, LI Gang, NAI Zida, LIU Di, JIANG Xinpeng. Research and Application of Gene-edited Probiotics in Animal Intestinal Health [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(3): 1016-1024. |
[7] | SHA Fangfang, FAN Pei, YANG Peichang, ZHANG Lu, LI Jianke. Generation of Mrjp1 Gene Knock-in Mice with Specific Expression in Vascular Smooth Muscle Cells via CRISPR/Cas9 Strategy [J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(11): 4392-4402. |
[8] | GAO Jiahao, QIAO Yanjie, LIAN Kexun, WANG Mengmeng, GU Xinli, SHAO Yongbin. Effects of Glycyrrhizic Acid on Immune Performance of Lipopolysaccharide-stressed Yellow Feather Broilers [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3419-3427. |
[9] | WANG Yue, ZHENG Yunxi, XU Songsong, XIANG Guangming, LI Hua, WANG Nan, FENG Zheng, LI Kui, MU Yulian. Regulation of Wip1 Gene on Animal Reproduction and Immunity [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(9): 3500-3507. |
[10] | NIE Jingru, MA Li, YAN Dawei, DENG Jun, ZHANG Hao, ZHANG Bo, LIU Jinqiao, DONG Xinxing. Analysis of Differentially Expressed Genes and Regulation Pathways of Intramuscular Fat Deposition in Large Diqing Tibetan Pigs at Different Growth Stages [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(8): 2855-2868. |
[11] | LIU Rui, LI Jiangling, DU Huarui, YANG Chaowu, CHEN Jialei, ZHAO Sujun, WANG Qiushi. Identification of Immune-Related circRNA of Thymus in Chickens [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(6): 2022-2032. |
[12] | WU Rifu, QU Hao, YAN Xia, LUO Chenglong, WANG Yan, SHU Dingming. Research Progress on the Genetic Regulation Mechanism of Feather Color Traits in Domestic Chickens [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(5): 1806-1816. |
[13] | ZHAI Zhe, CHEN Si, WU Yanru, WANG Xuemei, LI Chongrui, LIU Zhiyong, CHEN Qiaoling, WANG Fengyang, DU Li, LI Chang, JIN Ningyi. Analysis of Promoter Activity and Screening of Transcription Regulatory Elements of CCL19 Gene in Sheep [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(4): 1213-1222. |
[14] | SHI Zhuoyan, LIU Xiaoping, JI Xiang, CHU Xiaoran, HOU Junjie, SONG Zhen, LI Xiaoxia, YANG Youbing, ZHANG Guluan, WANG Jianping, WEN Fengyun. Developmental Changes of Muscle Fiber Histology and Myogenic Regulatory Genes with Different Slaughter Weights in Yuxi Black Pigs [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(12): 4582-4592. |
[15] | GUO Zimeng, WANG Fuzheng, WANG Chengzhi, DU Peng, ZHANG Mingyue, LI Zeyao, SU Xiaochen, WU Gaofeng, YANG Jiancheng. Effect of Taurine Additive Package on the Immune Function of Immunosuppressed Mice [J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(12): 4635-4645. |
Viewed | ||||||
Full text |
|
|||||
Abstract |
|
|||||