粪菌微生物移植在哺乳动物中的研究进展

doi:10.16431/j.cnki.1671-7236.2023.08.036

Abstract

Abstract: It contains a large number of microorganisms in the intestines of mammals such as mice,pigs,cattle,sheep,humans,etc.,which are essential for intestinal homeostasis and host health.Intestinal microbial disorders can lead to intestinal inflammation,nervous system diseases,functional and metabolic disorders and other diseases,which cause serious harm to animal and human health.Different species and breeds exhibit unique gut microbial characteristics,and the homeostatic balance of these microorganisms is important for animal health.At this stage,the research has found that fecal microbiota transplantation (FMT) plays an important role in restoring intestinal microbial dysregulation and intervening or reconstructing the balance of mammalian intestinal microbiota,and FMT is gradually widely used in infectious and non-infectious diseases.With the development of FMT technology,there is a new direction for the research whether mammals treat intestinal diseases by regulating microorganisms or other diseases,and this technical means is gradually widely used in various research fields.Based on the application of FMT in existing research areas,this review summarized the research progress on FMT widely used in the intestine and its related to diseases,so as to establish a more standardized,efficient,safe and beneficial FMT system for mammals,and provide new references and ideas for FMT in improving mammalian production performance,breeding and disease prevention.

Key words: microbial dysregulation; intestinal microbiota; fecal bacteria transplantation (FMT)

CLC Number:

S816.3

YAO Wenna, YAN Shuo, XUE Yue, ZHAO Yulong, SU He, SONG Yongli, LI Xihe, BAO Huala, BAO Siqin. Research Progress on Fecal Microbiota Transplantation in Mammals[J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(8): 3384-3390.

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Research Progress on Fecal Microbiota Transplantation in Mammals

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