牛病毒性腹泻病毒的分子生物学特性及发病机制研究进展

doi:10.16431/j.cnki.1671-7236.2023.11.031

Abstract

Abstract: Bovine viral diarrhea virus (BVDV) is one of the important pathogens affecting the cattle industry in the world, which has caused huge economic losses to animal husbandry.BVDV consists of two biological types and a variety of different genetic subtypes, which have different antigenicity, cytopathology and pathogenicity.Although countries around the world have made many efforts to control and prevent the occurrence and prevalence of BVDV, there are still reports of BVDV infection in animals.The author mainly discussed the molecular biology, pathogenesis and host immune response to viral infection, especially immune escape strategy, immune prevention and control of BVDV.Some immune escape strategies of BVDV by hijacking the host immune system to ensure successful replication of the virus were described, in order to provide reference for curbing the emergence and spread of BVDV, so as to achieve purification and control of the virus.

Key words: Bovine viral diarrhea virus; molecular biology; pathogenesis

CLC Number:

S858.23

HAN Mengli, ZHANG Qian, ZHAO Wenjuan, ZHANG Xingxing, WU Tongzhong, HUANG Xin, ZHONG Fagang. Advances on Molecular Biology and Pathogenesis of Bovine Viral Diarrhea Virus[J]. China Animal Husbandry and Veterinary Medicine, 2023, 50(11): 4632-4645.

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Advances on Molecular Biology and Pathogenesis of Bovine Viral Diarrhea Virus

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