雏鸡用水凝胶药物载体的研制

doi:10.16431/j.cnki.1671-7236.2022.10.040

Abstract

Abstract: 【Objective】 Through physical crosslinking method and characterization analysis,a kind of ready to use hydrogel with adding water and stirring was developed for chicks.【Method】 The hydrogel was prepared,and the formula was optimized by pre-experiment and Box-Behnken response surface method.Scanning electron microscope (SEM) was used to observe the micromorphology.Fourier transform infrared spectroscopy (FTIR) was used to judge the interaction between molecules according to the position shift of chemical group absorption peak,and the changes of physical and chemical properties were studied by differential scanning calorimetry (DSC).【Result】 The optimal formula of the hydrogel carrier was 4% sodium polyacrylate super absorbent resin,10% maltodextrin,1.5% guar gum,and water.SEM results showed that both super absorbent polymer and hydrogel had porous network structure,maltodextrin and guar gum had tighter structure and smaller cavity.FTIR showed that there were hydrogen bonding and intermolecular entanglement,and no new chemical groups were formed.DSC results showed that they were interacted with each other,their endothermic peaks were wider,their melting point was higher,and their thermal stability was improved.【Conclusion】 A hydrogel carrier for chicks was prepared with simple preparation method,low cost and convenient use.

Key words: chicks; hydrogel; response surface methodology

CLC Number:

S859

SUN Yuanyuan, LIANG Chuncai, ZHANG Hailong, LIU Juxiang. Preparation of Hydrogel Drug Carrier for Chicks[J]. China Animal Husbandry and Veterinary Medicine, 2022, 49(10): 4075-4084.

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Preparation of Hydrogel Drug Carrier for Chicks

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